DOK3

Gene Symbol DOK3
Entrez Gene 79930
Alt Symbol DOKL
Species Human
Gene Type protein-coding
Description docking protein 3
Other Description Dok-like protein|downstream of tyrosine kinase 3
Swissprots Q9H666 Q8N864 H7BXS0 Q7L591 Q9BQB3 E9PAT0
Accessions EAW84982 EAW84983 EAW84984 Q7L591 AK026223 BAB15399 AK097258 BAC04986 AK307300 AL583057 AL833678 BC004564 AAH04564 BC004867 AAH04867 BG756981 BI489608 CF138017 DA674730 DA931137 XM_005265984 XP_005266041 XM_005265985 XP_005266042 XM_005265987 XP_005266044 XM_011534654 XP_011532956 XM_011534655 XP_011532957 XM_011534656 XP_011532958 XM_011534657 XP_011532959 NM_001144875 NP_001138347 NM_001144876 NP_001138348 NM_001308235 NP_001295164 NM_001308236 NP_001295165 NM_024872 NP_079148
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Tissue Specificity Expressed in spleen. {ECO:0000269|PubMed:12595900}.

Dok-3 (F-7) - sc-390007 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dok-3 (F-7): sc-390007. Western blot analysis of Dok-3 expression in RAW 264.7 (A) and Jurkat (B) whole cell lysates.

Dok-3 (E-2) - sc-271132 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dok-3 (E-2): sc-271132. Western blot analysis of Dok-3 expression in RAW 264.7 whole cell lysate.

Dok-3 (H-206) - sc-33798 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Dok-3 (H-206): sc-33798. Western blot analysis of Dok-3 expression in Jurkat (A), CCRF-CEM (B), K-562 (C) and NIH/3T3 (D) whole cell lysates.

Dok-3 (G-6) - sc-271131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dok-3 (G-6): sc-271131. Western blot analysis of Dok-3 expression in RAW 264.7 whole cell lysate.

Dok-3 (G-18) - sc-323798 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Dok-3 (N-20) - sc-323797 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Dok-3 (M-214) - sc-33797 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Dok-3 (M-214): sc-33797. Western blot analysis of Dok-3 expression in mouse PBL whole cell lysate.

Anti-DOK3 antibody - ab118823 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-DOK3 antibody (ab118823) at 0.1 µg/ml + Human PBMC lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-DOK3 antibody - ab1357 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-DOK3 antibody (ab1357) at 0.1 µg/ml + Human PBMC lysate (RIPA buffer) at 35 µg

Anti-DOK3 antibody - ab89327 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-DOK3 antibody (ab89327) at 1 µg/ml + human liver tissue lysate at 50 µg

Anti-DOK3 antibody - ab97297 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-DOK3 antibody (ab97297) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-DOK3 antibody - ab135965 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-DOK3 antibody (ab135965) at 1/500 dilution + K562 cell lysate at 30 µg

Anti-DOK3 antibody - C-terminal - ab170798 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Formalin/PFA-fixed paraffin-embedded Human lung tissue labeling DOK3 with ab170798 at a 1/10 dilution followed by peroxidase conjugation of the secondary antibody and DAB staining.

Anti-DOK3 Antibody (aa484-496) IHC-plus™ - LS-B5699 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-DOK3 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5699 concentration 6.125 ug/ml.

Anti-DOK3 Antibody (aa293-321) - LS-C167501 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DOK3 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human lung tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-DOK3 Antibody (aa181-271) - LS-C143823 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DOK3 Antibody (aa293-321, AP) - LS-C234729 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK3 Antibody (aa293-321, Biotin) - LS-C234730 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK3 Antibody (aa293-321, APC) - LS-C234731 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK3 Antibody (aa293-321, FITC) - LS-C234732 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK3 Antibody (aa293-321, PE) - LS-C234734 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK3 Antibody (aa293-321, Azide-free, HRP) - LS-C249862 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK3 Antibody (aa101-150) - LS-C119115 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HepG2 cells, using DOK3 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-DOK3 Antibody (aa434-496) - LS-C185912 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: A431 . 10% SDS PAGE. DOK3 antibody diluted at 1:1000.

Anti-DOK3 Antibody (aa298-347) - LS-C291891 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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