Gene Symbol | DOK3 |
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Entrez Gene | 79930 |
Alt Symbol | DOKL |
Species | Human |
Gene Type | protein-coding |
Description | docking protein 3 |
Other Description | Dok-like protein|downstream of tyrosine kinase 3 |
Swissprots | Q9H666 Q8N864 H7BXS0 Q7L591 Q9BQB3 E9PAT0 |
Accessions | EAW84982 EAW84983 EAW84984 Q7L591 AK026223 BAB15399 AK097258 BAC04986 AK307300 AL583057 AL833678 BC004564 AAH04564 BC004867 AAH04867 BG756981 BI489608 CF138017 DA674730 DA931137 XM_005265984 XP_005266041 XM_005265985 XP_005266042 XM_005265987 XP_005266044 XM_011534654 XP_011532956 XM_011534655 XP_011532957 XM_011534656 XP_011532958 XM_011534657 XP_011532959 NM_001144875 NP_001138347 NM_001144876 NP_001138348 NM_001308235 NP_001295164 NM_001308236 NP_001295165 NM_024872 NP_079148 |
Function | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. |
Tissue Specificity | Expressed in spleen. {ECO:0000269|PubMed:12595900}. |
DOK3 - MBS1270368 from MyBioSource
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Human DOK3 cDNA clone(NM_001144875.1) - CDFH005354 from Creative Biomart
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Human DOK3 cDNA clone(NM_001144876.1) - CDFH005355 from Creative Biomart
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Human DOK3 ORF Clone(NM_024872.2) - CDCL161409 from Creative Biomart
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Human DOK3 ORF Clone(NM_001144875.1) - CDCL161410 from Creative Biomart
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Human DOK3 ORF Clone(NM_001144875.1) - CDCL161411 from Creative Biomart
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Human DOK3 ORF Clone(NM_001144875.1) - CDCR352074 from Creative Biomart
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Human DOK3 ORF Clone(NM_001144875.1) - CDCR352075 from Creative Biomart
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Human DOK3 ORF Clone(NM_001144876.1) - CDCR352076 from Creative Biomart
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Human DOK3 ORF Clone(NM_001144876.1) - CDCR352084 from Creative Biomart
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Mouse Dok3 ORF Clone(NM_013739.2) - CDCR252302 from Creative Biomart |
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Human DOK3 ORF clone (NM_001144875.1) - CDCR056902 from Creative biogene
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Human DOK3 ORF clone (NM_001144876.1) - CDCR056904 from Creative biogene
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Human DOK3 ORF Clone (BC004564) - CDCS408411 from Creative biogene
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Human DOK3 cDNA Clone(NM_001144875.1) - CDFH005354 from Creative biogene
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Human DOK3 cDNA Clone(NM_001144876.1) - CDFH005355 from Creative biogene
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