DOK3

Gene Symbol DOK3
Entrez Gene 79930
Alt Symbol DOKL
Species Human
Gene Type protein-coding
Description docking protein 3
Other Description Dok-like protein|downstream of tyrosine kinase 3
Swissprots Q9H666 Q8N864 H7BXS0 Q7L591 Q9BQB3 E9PAT0
Accessions EAW84982 EAW84983 EAW84984 Q7L591 AK026223 BAB15399 AK097258 BAC04986 AK307300 AL583057 AL833678 BC004564 AAH04564 BC004867 AAH04867 BG756981 BI489608 CF138017 DA674730 DA931137 XM_005265984 XP_005266041 XM_005265985 XP_005266042 XM_005265987 XP_005266044 XM_011534654 XP_011532956 XM_011534655 XP_011532957 XM_011534656 XP_011532958 XM_011534657 XP_011532959 NM_001144875 NP_001138347 NM_001144876 NP_001138348 NM_001308235 NP_001295164 NM_001308236 NP_001295165 NM_024872 NP_079148
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Tissue Specificity Expressed in spleen. {ECO:0000269|PubMed:12595900}.

Dok-3 CRISPR/Cas9 KO Plasmid (h) - sc-404131 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-3 HDR Plasmid (h) - sc-404131-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-3 Double Nickase Plasmid (h) - sc-404131-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-3 Double Nickase Plasmid (h2) - sc-404131-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-3 CRISPR Activation Plasmid (h) - sc-404131-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-3 CRISPR Activation Plasmid (h2) - sc-404131-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-3 Lentiviral Activation Particles (h) - sc-404131-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-3 Lentiviral Activation Particles (h2) - sc-404131-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-3 siRNA (h) - sc-44762 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dok-3 shRNA Plasmid (h) - sc-44762-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dok-3 shRNA (h) Lentiviral Particles - sc-44762-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU124381 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7429 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7429 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01817 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01817

DOK3 siRNA (Human) - CRJ2673 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DOK3 - MBS8239388 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DOK3 (NM_024872.2) - SHH280293 from Creative biogene

Category siRNA
Species Reactivities Human

DOK3 shRNA Plasmid (Human) - CHJ2673 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DOK3 miRNA 3'UTR clone - MiUTR3H-11884 from Creative biogene

Species Reactivities Human

DOK3 miRNA 3'UTR clone - MiUTR3H-11885 from Creative biogene

Species Reactivities Human

DOK3 miRNA 3'UTR clone - MiUTR3H-11886 from Creative biogene

Species Reactivities Human
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