Gene Symbol | DOK3 |
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Entrez Gene | 79930 |
Alt Symbol | DOKL |
Species | Human |
Gene Type | protein-coding |
Description | docking protein 3 |
Other Description | Dok-like protein|downstream of tyrosine kinase 3 |
Swissprots | Q9H666 Q8N864 H7BXS0 Q7L591 Q9BQB3 E9PAT0 |
Accessions | EAW84982 EAW84983 EAW84984 Q7L591 AK026223 BAB15399 AK097258 BAC04986 AK307300 AL583057 AL833678 BC004564 AAH04564 BC004867 AAH04867 BG756981 BI489608 CF138017 DA674730 DA931137 XM_005265984 XP_005266041 XM_005265985 XP_005266042 XM_005265987 XP_005266044 XM_011534654 XP_011532956 XM_011534655 XP_011532957 XM_011534656 XP_011532958 XM_011534657 XP_011532959 NM_001144875 NP_001138347 NM_001144876 NP_001138348 NM_001308235 NP_001295164 NM_001308236 NP_001295165 NM_024872 NP_079148 |
Function | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. |
Tissue Specificity | Expressed in spleen. {ECO:0000269|PubMed:12595900}. |
Human DOK3 full length protein - ab164161 from Abcam
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Human DOK3 peptide - ab22816 from Abcam
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DOK3 Antibody Blocking Peptide - LS-E1384 from LifeSpan Bioscience
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DOK3 Antibody Blocking Peptide - LS-E25254 from LifeSpan Bioscience
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DOK3 Recombinant Protein - H00079930-P01 from Novus Biologicals
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DOK3-Antibody-C-term-Blocking-peptide - BP12040b from Abgent, a WuXi AppTec company
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DOK3 blocking peptide - GTX21357-PEP from GeneTex
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Goat anti DOK3 antibody Immunizing peptide - orb17383 from Biorbyt
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DOK3 Peptide - AC21-0082-P from Abcore
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DOK3 - H00079930-P01 from Acris Antibodies
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DOK3 Peptide - 45-490P from ProSci
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DOK3 fusion protein - Ag8237 from Proteintech Group
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DOK3 fusion protein - ag8221 from Proteintech Group
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Recombinant Human DOK3, His-tagged - DOK3-12128H from Creative Biomart
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Recombinant Docking Protein 3 (DOK3) - RPF373Hu01 from Uscn Life Science Inc.
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Recombinant Docking Protein 3 (DOK3) - RPF373Mu01 from Uscn Life Science Inc.
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Recombinant Docking Protein 3 (DOK3) - RPF373Ra01 from Uscn Life Science Inc.
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Recombinant Docking Protein 3 (DOK3) - RPF373Hu01 from Cloud-clone
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Recombinant Human Docking protein 3(DOK3) - CSB-YP007109HU CSB-EP007109HU CSB-BP007109HU CSB-MP007109HU from Cusabio
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DOK3 Protein - abx163686 from Abbexa
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DOK3 (transcript variant 1) - TP322370 from Acris Antibodies
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DOK3, Peptide - MBS426671 from MyBioSource
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DOK3 Peptide, Human - M34GP04485H from Creative Peptides
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DOK3 Recombinant Protein (OPCD02782) - OPCD02782 from Aviva Systems Biology
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Docking protein 3 (DOK3), Recombinant Protein - MBS1436550 from MyBioSource
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