SRGN

Gene Symbol	SRGN
Entrez Gene	5552
Alt Symbol	PPG, PRG, PRG1
Species	Human
Gene Type	protein-coding
Description	serglycin
Other Description	hematopoetic proteoglycan core peptide|hematopoetic proteoglycan core protein|hematopoietic proteoglycan core protein|p.PG|platelet proteoglycan core protein|proteoglycan 1, secretory granule|proteoglycan protein core for mast cell secretory granule|secretory granule proteoglycan core peptide|secretory granule proteoglycan core protein|serglycin proteoglycan
Swissprots	Q5VW06 B2R4L7 P10124
Accessions	AAA60322 EAW54309 EAW54310 P10124 AI347627 AK311873 BAG34814 BC015516 AAH15516 BC022313 BG057351 BG548665 BP335278 BQ051861 CA308463 CB110512 CD677686 D28395 BAA05761 DQ891442 ABM82368 DQ894620 ABM85546 J03223 AAA60179 X12765 CAA31255 X17042 CAA34900 NM_002727 NP_002718 NR_036430
Function	Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF- alpha and may also regulate protease secretion. Inhibits bone mineralization. {ECO:0000269|PubMed:11911826, ECO:0000269|PubMed:16420477, ECO:0000269|PubMed:16870619}.
Subcellular Location	Cytoplasmic granule {ECO:0000250}. Secreted, extracellular space. Golgi apparatus. Note=Found in mast cell granules and in cytoplasmic granules of cytolytic T lymphocytes from where it is secreted upon cell activation. Secreted constitutively by endothelial cells and macrophages. Located to Golgi apparatus during neutrophil differentiation.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SRGN / Serglycin ELISA Kit (Sandwich ELISA) - LS-F6529 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Human SRGN / Serglycin ELISA Kit (Sandwich ELISA) - LS-F12657 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Serglycin (SRGN), Human, ELISA Kit - CSB-EL022664HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Serglycin (SRGN), Human, ELISA Kit - SEC869Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.064ng/mL Range 0.156-10ng/mL

Serglycin, SRGN, Human, ELISA Kit - E1072h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Serglycin, ELISA Kit - MBS104116 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

serglycin, ELISA Kit - MBS910006 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.078 ng/ml. Range 0.312 ng/ml -20 ng/ml.

Serglycin, ELISA Kit - MBS063225 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serglycin, ELISA Kit - MBS103163 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serglycin (SRGN), ELISA Kit - MBS2023281 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.055ng/mL. Range 0.156-10ng/mL

Serglycin, ELISA Kit - MBS103694 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/ml. Range 0.625 ng/ml - 20 ng/ml.

Serglycin, ELISA Kit - MBS056360 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serglycin, ELISA Kit - MBS070002 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serglycin, ELISA Kit - MBS095604 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Serglycin (SRGN) - SEC869Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.055ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Serglycin(SRGN) ELISA kit - CSB-EL022664HU from Cusabio Category ELISA Kit Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

ELISA Kit for Immediate Early Response 3 (IER3) - SEG249Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Serglycin (SRGN) - SEC869Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.055ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Rat SRGN / Serglycin ELISA Kit (Custom ELISA) - LS-F15893 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Mouse SRGN / Serglycin ELISA Kit (Custom ELISA) - LS-F15892 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Human Serglycin (SRGN) ELISA Kit - EKU07280 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.059 ng/mL Range 0.156-10 ng/mL

Human Serglycin ELISA Kit - abx250462 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human Serglycin ELISA Kit - abx153063 from Abbexa Category ELISA Kit Sensitivity 0.062 ng/ml Range 0.156 ng/ml - 10 ng/ml

Serglycin (SRGN), Human, ELISA Kit - DL-SRGN-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human SRGN(Serglycin) ELISA Kit - E-EL-H2508 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

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