TWIST2

Gene Symbol	TWIST2
Entrez Gene	117581
Alt Symbol	DERMO1, FFDD3, SETLSS, bHLHa39
Species	Human
Gene Type	protein-coding
Description	twist family bHLH transcription factor 2
Other Description	class A basic helix-loop-helix protein 39|dermis-expressed protein 1|twist basic helix-loop-helix transcription factor 2|twist homolog 2|twist-related bHLH protein Dermo1|twist-related protein 2
Swissprots	Q8WVJ9 Q3SYL6
Accessions	EAW71163 EAW71164 Q8WVJ9 AW072674 BC017907 AAH17907 BC033168 AAH33168 BC103755 AAI03756 BU615717 DB359681 DQ892806 ABM83732 DQ896053 ABM87052 XM_006712242 XP_006712305 NM_001271893 NP_001258822 NM_057179 NP_476527
Function	Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism (By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors. {ECO:0000250, ECO:0000269|PubMed:11062344}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981, ECO:0000269|PubMed:11062344}. Cytoplasm {ECO:0000269|PubMed:11062344}. Note=Mainly nuclear during embryonic development. Cytoplasmic in adult tissues.
Tissue Specificity	In the embryo, highly expressed in chondrogenic cells. In embryonic skin, expressed in the undifferentiated mesenchymal layer beneath the epidermis which later develops into the dermis. Expressed in early myeloid cells but not in lymphoid cells in the liver. Expression also detected in the secretory ependymal epithelium of the choroid plexus primordium. In the adult, expressed in secreting glandular tissues and tubules. {ECO:0000269|PubMed:11062344}.
Top Pathways	Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TWIST2 (Human) IP-WB Antibody Pair - H00117581-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

TWIST2 (Human) IP-WB Antibody Pair - H00117581-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

twist homolog 2 (Drosophila) , ELISA Kit - MBS9320762 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.625ng/ml-20ng/ml.

Human TWIST2 ELISA Kit - E101635 from Biobool Category ELISA Kit

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9369460 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9346784 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9343896 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9358205 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9359597 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9366995 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9350602 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9345693 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9364481 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9350875 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9362357 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9354732 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9346732 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9359426 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9359334 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9357742 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9373076 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9354630 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9364176 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9352732 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Twist-Related Protein 2 (TWIST2), ELISA Kit - MBS9352229 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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