EIF4EBP1

Gene Symbol	EIF4EBP1
Entrez Gene	1978
Alt Symbol	4E-BP1, 4EBP1, BP-1, PHAS-I
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 4E binding protein 1
Other Description	eIF4E-binding protein 1|eukaryotic translation initiation factor 4E-binding protein 1|phosphorylated heat- and acid-stable protein regulated by insulin 1
Swissprots	Q6IBN3 Q13541 B2R502 D3DSW8
Accessions	CCW44094 EAW63341 EAW63342 Q13541 AB044548 BAB18650 AK312011 BAG34949 BC004459 AAH04459 BC058073 AAH58073 BF964628 BT007162 AAP35826 CR456769 CAG33050 DQ890570 ABM92187 DQ893731 ABM84657 L36055 AAA62269 NM_004095 NP_004086
Function	Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. {ECO:0000269|PubMed:22578813, ECO:0000269|PubMed:7935836}.
Top Pathways	RNA transport, Choline metabolism in cancer, AMPK signaling pathway, PI3K-Akt signaling pathway, ErbB signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-EIF4EBP1-cDNA-Clone - DC01492 from Abgent, a WuXi AppTec company Prices $159.30 Sizes 10 µg Species Human Accession BC004459

EIF4EBP1 - MBS1277863 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC004459

Human EIF4EBP1 ORF Clone(NM_004095.3) - CDCL162176 from Creative Biomart Species Human Accession NM_004095.3

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone in cloning vector - HG10022-M from Sino Biological Species Human

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10022-ACG from Sino Biological Species Human

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10022-NF from Sino Biological Species Human

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10022-CF from Sino Biological Species Human

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10022-NM from Sino Biological Species Human

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10022-CM from Sino Biological Species Human

Human 4EBP1 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG10022-M-F from Sino Biological Species Human Accession NM_004095.3

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10022-NH from Sino Biological Species Human

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10022-ACR from Sino Biological Species Human

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10022-ANR from Sino Biological Species Human

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10022-ANG from Sino Biological Species Human

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10022-CY from Sino Biological Species Human

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10022-CH from Sino Biological Species Human

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid - HG10022-UT from Sino Biological Species Human

Human 4E-BP1/EIF4EBP1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10022-NY from Sino Biological Species Human

4EBP1 - CL01024H01 from Elabscience Species Human Accession NM_004095.3

Human 4EBP1 ORF clone(NM_004095.3) - CDCL182505 from Creative biogene Species Human

Human EIF4EBP1 ORF Clone (BC004459) - CDCS411605 from Creative biogene Species Human Accession Q13541

Human 4E-BP1 Gene - orb90644 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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