EIF4EBP1

Gene Symbol	EIF4EBP1
Entrez Gene	1978
Alt Symbol	4E-BP1, 4EBP1, BP-1, PHAS-I
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 4E binding protein 1
Other Description	eIF4E-binding protein 1|eukaryotic translation initiation factor 4E-binding protein 1|phosphorylated heat- and acid-stable protein regulated by insulin 1
Swissprots	Q6IBN3 Q13541 B2R502 D3DSW8
Accessions	CCW44094 EAW63341 EAW63342 Q13541 AB044548 BAB18650 AK312011 BAG34949 BC004459 AAH04459 BC058073 AAH58073 BF964628 BT007162 AAP35826 CR456769 CAG33050 DQ890570 ABM92187 DQ893731 ABM84657 L36055 AAA62269 NM_004095 NP_004086
Function	Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. {ECO:0000269|PubMed:22578813, ECO:0000269|PubMed:7935836}.
Top Pathways	RNA transport, Choline metabolism in cancer, AMPK signaling pathway, PI3K-Akt signaling pathway, ErbB signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human eIF4EBP1 peptide - ab39917 from Abcam Category Peptide Prices $181.00 Sizes 50 µg Species Human

Human eIF4EBP1 full length protein - ab89849 from Abcam Category Protein Source E. coli Species Human

Human eIF4EBP1 full length protein - ab85248 from Abcam Category Protein Source E. coli Species Human

Human eIF4EBP1 full length protein - ab60007 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

EIF4EBP1 / 4EBP1 Antibody Blocking Peptide - LS-E1818 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EIF4EBP1 / 4EBP1 Antibody Blocking Peptide - LS-E30143 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

EIF4EBP1 / 4EBP1 Antibody Blocking Peptide - LS-E6785 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EIF4EBP1 / 4EBP1 Antibody Blocking Peptide - LS-E7371 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EIF4EBP1 / 4EBP1 Antibody Blocking Peptide - LS-E18672 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

4EBP1 Recombinant Protein - H00001978-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human 4EBP1 Protein - NBP1-30218 from Novus Biologicals Category Protein Prices $229.00 Sizes 100 µg Source E.coli Species Human

4EBP1 Blocking Peptide - NBP1-76621PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

4EBP1 Peptide - P0772 from Novus Biologicals Category Peptide Species Human

4EBP1 Peptide - P0770 from Novus Biologicals Category Peptide Species Human

4EBP1 Peptide - P1552 from Novus Biologicals Category Peptide Species Human

EIF4EBP1-Antibody-Center-Blocking-peptide - BP12627c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

EIF4EBP1-Antibody-T69-Blocking-Peptide - BP1981c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

EIF4EBP1-Antibody-S100-Blocking-Peptide - BP1981a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Phospho-EIF4EBP1T36-Antibody-Blocking-peptide - BP3417a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

4E-BP1 Protein - GTX116315-pro from GeneTex Category Protein Prices $299.00 Sizes 10 μg Source E. coli Species Human

EIF4EBP1 Protein (OPPA01419) - OPPA01419 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg Source E. Coli

Human EIF4EBP1 protein - orb81082 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 10 μg, 50 μg Species Human

Human 4EBP1 protein - orb49370 from Biorbyt Category Protein Prices $323.00, $485.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human BP-1 protein - orb80971 from Biorbyt Category Protein Prices $366.00, $400.00, $612.00 Sizes 5 μg, 2 μg, 10 μg Species Human

Human 4EBP1 His tag protein - orb84035 from Biorbyt Category Protein Prices $323.00, $434.00 Sizes 50 μg, 100 μg Source E. coli Species Human

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