TNRC6B
| Gene Symbol | TNRC6B |
|---|---|
| Entrez Gene | 23112 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | trinucleotide repeat containing 6B |
| Other Description | trinucleotide repeat-containing gene 6B protein |
| Swissprots | B0QY78 B0QY73 B4DGC0 Q9UPQ9 Q5TH52 Q8TBX2 |
| Accessions | EAW60367 EAW60368 EAW60369 EAW60370 EAW60371 EAW60372 EAW60373 Q9UPQ9 AB029016 BAA83045 AK294519 BAG57731 AK296590 BAG59207 AK304087 BAG64993 AL831862 BC028626 AAH28626 BC046218 BE501815 BG942870 BQ009349 BU584176 BX537577 BX647630 BX952326 CA312515 DB147781 NM_001024843 NP_001020014 NM_001162501 NP_001155973 NM_015088 NP_055903 |
| Function | Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes. {ECO:0000269|PubMed:16289642, ECO:0000269|PubMed:19167051, ECO:0000269|PubMed:19304925, ECO:0000269|PubMed:21981923}. |
| Subcellular Location | Cytoplasm, P-body {ECO:0000269|PubMed:16289642, ECO:0000269|PubMed:19167051}. Note=Mammalian P-bodies are also known as GW bodies (GWBs). |
TNRC6B (C-14) - sc-86913 from Santa Cruz Biotechnology
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TNRC6B (P-15) - sc-86914 from Santa Cruz Biotechnology
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Anti-TNRC6B Antibody (clone 4B11) - LS-C139220 from LifeSpan Bioscience
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Anti-TNRC6B Antibody (aa180-229) - LS-C101833 from LifeSpan Bioscience
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Anti-TNRC6B Antibody (aa396-445) - LS-C110569 from LifeSpan Bioscience
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TNRC6B Antibody - NBP1-57549 from Novus Biologicals
![Western Blot: TNRC6B Antibody [NBP1-57549] - Human Brain lysate, concentration 0.2-1 ug/ml.](http://www.bioprodhub.com/system/product_images/ab_products/5/sub_10/7292_TNRC6B%2520Antibody-Western%2520Blot-NBP1-57549-img0002.jpg)
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TNRC6B Antibody - NBP1-57461 from Novus Biologicals
![Western Blot: TNRC6B Antibody [NBP1-57461] - Human Muscle lysate, concentration 0.2-1 ug/ml.](http://www.bioprodhub.com/system/product_images/ab_products/5/sub_10/16977_TNRC6B%2520Antibody-Western%2520Blot-NBP1-57461-img0002.jpg)
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TNRC6B Antibody - NBP1-81442 from Novus Biologicals
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TNRC6B Antibody (4B11) - H00023112-M02 from Novus Biologicals
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TNRC6B Polyclonal Antibody - bs-11489R from Bioss
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TNRC6B Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11489R-A350 from Bioss
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TNRC6B Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11489R-A488 from Bioss
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TNRC6B Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11489R-A555 from Bioss
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TNRC6B Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11489R-A647 from Bioss
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TNRC6B Polyclonal Antibody, Cy3 Conjugated - bs-11489R-Cy3 from Bioss
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TNRC6B Polyclonal Antibody, Cy5 Conjugated - bs-11489R-Cy5 from Bioss
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TNRC6B Polyclonal Antibody, Cy5.5 Conjugated - bs-11489R-Cy5.5 from Bioss
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TNRC6B Polyclonal Antibody, Cy7 Conjugated - bs-11489R-Cy7 from Bioss
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TNRC6B Polyclonal Antibody, FITC Conjugated - bs-11489R-FITC from Bioss
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TNRC6B Polyclonal Antibody, Biotin Conjugated - bs-11489R-Biotin from Bioss
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TNRC6B Polyclonal Antibody, HRP Conjugated - bs-11489R-HRP from Bioss
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Anti-TNRC6B antibody produced in rabbit - SAB2102507 from Sigma-Aldrich
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Anti-TNRC6B antibody produced in rabbit - HPA003180 from Sigma-Aldrich
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Anti-TNRC6B, (N-terminal) antibody produced in rabbit - SAB2103184 from Sigma-Aldrich
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TNRC6B antibody - N-terminal region (ARP40317_P050) - ARP40317_P050 from Aviva Systems Biology
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