GPR75

Gene Symbol	GPR75
Entrez Gene	10936
Alt Symbol	GPRchr2, WI31133
Species	Human
Gene Type	protein-coding
Description	G protein-coupled receptor 75
Other Description	probable G-protein coupled receptor 75
Swissprots	Q6NWR2 O95800 B2RC02
Accessions	AAD22770 AAY15018 EAX00162 O95800 AF072693 AAD19849 AK314885 BAG37399 BC067475 AAH67475 BC067476 AAH67476 NM_006794 NP_006785
Function	G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor. {ECO:0000250|UniProtKB:Q6X632, ECO:0000303|PubMed:23979485}.
Subcellular Location	Cell membrane; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity	Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer. Also expressed by islet cells (at protein level). {ECO:0000269|PubMed:10381362, ECO:0000269|PubMed:11466257, ECO:0000269|PubMed:23979485}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GPR75 Antibody Blocking Peptide - LS-E4830 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPR75 Antibody Blocking Peptide - LS-E12050 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPR75 Antibody Blocking Peptide - LS-E28708 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR75 Antibody Blocking Peptide - LS-E28709 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR75 Antibody Blocking Peptide - LS-E28710 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR75 Antibody Blocking Peptide - LS-E11664 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPR75 Antibody Blocking Peptide - LS-E11665 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPR75 Antibody Blocking Peptide - LS-E28346 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR75 Antibody Blocking Peptide - LS-E28345 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR75 Antibody Blocking Peptide - LS-E28341 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR75 Antibody Blocking Peptide - LS-E28343 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR75 Antibody Blocking Peptide - LS-E28344 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human GPR75 Protein - H00010936-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

GPR75-Antibody-C-term-Blocking-Peptide - BP17211b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GPR75 Blocking Peptide - 33R-7365 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GPR75 Blocking Peptide - 33R-3513 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GPR75 Blocking Peptide - 33R-1380 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GPR75 Blocking Peptide - abx063715 from Abbexa Category Peptide Species Human, Mouse, Rat

GPR75 - H00010936-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

GPR75 Control Peptide - AP10095CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 250 µg

GPR75 fusion protein - Ag12053 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

GPR75 fusion protein - ag11835 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human GPR75, His-tagged - GPR75-13487H from Creative Biomart Category Protein Source E.coli Species Human

GPR75 Blocking Peptide - CBP2521 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

GPR75 Peptide - BS5752P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

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