Gene Symbol | ESRP1 |
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Entrez Gene | 54845 |
Alt Symbol | RBM35A, RMB35A |
Species | Human |
Gene Type | protein-coding |
Description | epithelial splicing regulatory protein 1 |
Other Description | RNA binding motif protein 35A|RNA-binding motif protein 35A|RNA-binding protein 35A |
Swissprots | Q499G3 A8MPX1 Q9NXL8 E9PB47 A6NHA8 Q2M2B0 Q6PJ86 Q6NXG1 |
Accessions | EAW91720 EAW91721 Q6NXG1 AI990751 AK000178 BAA90992 AK001805 BC019932 AAH19932 BC035406 BC052574 BC067098 AAH67098 BC099916 AAH99916 BC101621 BC112043 AAI12044 BG182742 BG212336 BX641160 BX647570 XM_005250991 XP_005251048 XM_005250992 XP_005251049 XR_242393 NM_001034915 NP_001030087 NM_001122825 NP_001116297 NM_001122826 NP_001116298 NM_001122827 NP_001116299 NM_017697 NP_060167 |
Function | mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. {ECO:0000269|PubMed:19285943}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19285943}. |
Tissue Specificity | Epithelial cell-specific. {ECO:0000269|PubMed:19285943}. |
RBM35A (Q-25) - sc-133945 from Santa Cruz Biotechnology
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RBM35A (N-18) - sc-98100 from Santa Cruz Biotechnology
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RBM35A (Q-18) - sc-98101 from Santa Cruz Biotechnology
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Anti-RBM35A antibody - ab107278 from Abcam
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Anti-ESRP1 / RBM35A Antibody (aa189-219, APC) - LS-C235073 from LifeSpan Bioscience
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Anti-ESRP1 / RBM35A Antibody (aa189-219, Biotin) - LS-C235074 from LifeSpan Bioscience
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Anti-ESRP1 / RBM35A Antibody (aa161-210) - LS-C82450 from LifeSpan Bioscience
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Anti-ESRP1 / RBM35A Antibody (aa189-219, AP) - LS-C235075 from LifeSpan Bioscience
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Anti-ESRP1 / RBM35A Antibody (aa189-219, FITC) - LS-C235076 from LifeSpan Bioscience
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Anti-ESRP1 / RBM35A Antibody (aa189-219, Azide-free, HRP) - LS-C249937 from LifeSpan Bioscience
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Anti-ESRP1 / RBM35A Antibody (aa189-219) - LS-C321203 from LifeSpan Bioscience
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Anti-ESRP1 / RBM35A Antibody (clone 27H12) - LS-C154126 from LifeSpan Bioscience
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Anti-ESRP1 / RBM35A Antibody (aa189-219, PE) - LS-C235080 from LifeSpan Bioscience
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Anti-ESRP1 / RBM35A Antibody (aa182-211) - LS-C167832 from LifeSpan Bioscience
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Anti-ESRP1 / RBM35A Antibody (N-Terminus) IHC-plus⢠- LS-B7036 from LifeSpan Bioscience
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ESRP1 Antibody - NBP1-82201 from Novus Biologicals
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ESRP1 Antibody - NBP1-82202 from Novus Biologicals
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ESRP1 Antibody - NBP1-76536 from Novus Biologicals
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ESRP1 Antibody - H00054845-B01P from Novus Biologicals
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Anti-RBM35A antibody produced in rabbit - AV42489 from Sigma-Aldrich
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Anti-ESRP1 antibody produced in rabbit - HPA023720 from Sigma-Aldrich
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Anti-RBM35A antibody produced in mouse - SAB1407580 from Sigma-Aldrich
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Anti-ESRP1 antibody produced in rabbit - HPA023719 from Sigma-Aldrich
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Anti-RBM35A antibody produced in rabbit - SAB3500968 from Sigma-Aldrich
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RBM35A antibody - N-terminal region (ARP42489_T100) - ARP42489_T100 from Aviva Systems Biology
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