Gene Symbol | ESRP1 |
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Entrez Gene | 54845 |
Alt Symbol | RBM35A, RMB35A |
Species | Human |
Gene Type | protein-coding |
Description | epithelial splicing regulatory protein 1 |
Other Description | RNA binding motif protein 35A|RNA-binding motif protein 35A|RNA-binding protein 35A |
Swissprots | Q499G3 A8MPX1 Q9NXL8 E9PB47 A6NHA8 Q2M2B0 Q6PJ86 Q6NXG1 |
Accessions | EAW91720 EAW91721 Q6NXG1 AI990751 AK000178 BAA90992 AK001805 BC019932 AAH19932 BC035406 BC052574 BC067098 AAH67098 BC099916 AAH99916 BC101621 BC112043 AAI12044 BG182742 BG212336 BX641160 BX647570 XM_005250991 XP_005251048 XM_005250992 XP_005251049 XR_242393 NM_001034915 NP_001030087 NM_001122825 NP_001116297 NM_001122826 NP_001116298 NM_001122827 NP_001116299 NM_017697 NP_060167 |
Function | mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. {ECO:0000269|PubMed:19285943}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19285943}. |
Tissue Specificity | Epithelial cell-specific. {ECO:0000269|PubMed:19285943}. |
Human RBM35A full length protein - ab162859 from Abcam
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ESRP1 / RBM35A Antibody Blocking Peptide - LS-E8051 from LifeSpan Bioscience
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ESRP1 / RBM35A Antibody Blocking Peptide - LS-E31078 from LifeSpan Bioscience
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Recombinant Human ESRP1 Protein - H00054845-P01 from Novus Biologicals
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ESRP1 Blocking Peptide - NBP1-76536PEP from Novus Biologicals
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ESRP1-Antibody-N-term-Blocking-peptide - BP5940a from Abgent, a WuXi AppTec company
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RBM35A Blocking Peptide - 33R-6542 from Fitzgerald
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ESRP1 / RBM35A - H00054845-P01 from Acris Antibodies
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ESRP1 / RBM35A control peptide - AP26107CP-N from Acris Antibodies
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RBM35A Peptide - 6185P from ProSci
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ESRP1 fusion protein - Ag16537 from Proteintech Group
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ESRP1 fusion protein - ag15386 from Proteintech Group
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Recombinant Human ESRP1, His-tagged - ESRP1-12559H from Creative Biomart
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Recombinant Human Epithelial splicing regulatory protein 1(ESRP1) - CSB-YP007832HU CSB-EP007832HU CSB-BP007832HU CSB-MP007832HU from Cusabio
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ESRP1 / RBM35A (transcript variant 1) - TP309131 from Acris Antibodies
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ESRP1 / RBM35A (transcript variant 2) - TP310539 from Acris Antibodies
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ESRP1 Protein - NBP1-82202PEP from Novus Biologicals
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ESRP1 Recombinant Protein Antigen - NBP1-82201PEP from Novus Biologicals
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ESRP1 Peptide, Human - M34GP05084H from Creative Peptides
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ESRP1 Recombinant Protein Antigen - NBP2-57822PEP from Novus Biologicals
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Epithelial splicing regulatory protein 1 (ESRP1), Recombinant Protein - MBS1384352 from MyBioSource
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Recombinant Human ESRP1 Protein (Met1-Ile681), His-tagged - ESRP1-587H from Creative Biomart
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