ADAMTS5

Gene Symbol	ADAMTS5
Entrez Gene	11096
Alt Symbol	ADAM-TS 11, ADAM-TS 5, ADAM-TS5, ADAMTS-11, ADAMTS-5, ADAMTS11, ADMP-2
Species	Human
Gene Type	protein-coding
Description	ADAM metallopeptidase with thrombospondin type 1 motif, 5
Other Description	A disintegrin and metalloproteinase with thrombospondin motifs 5|a disintegrin and metalloproteinase with thrombospondin motifs 11|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)|aggrecanase-2
Swissprots	Q9UKP2 Q9UNA0 Q52LV4
Accessions	BAA95503 BAA95504 EAX09948 EAX09949 Q9UNA0 AF086299 AF086358 AF141293 AAF02493 AF142099 AAD49577 AK094057 AK095905 BC093775 AAH93775 BC093777 AAH93777 XM_011529448 XP_011527750 NM_007038 NP_008969
Function	Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Tissue Specificity	Expressed at low level in placenta primarily but also detected in heart and brain, cervix, uterus, bladder, esophagus, rib cartilage, chondroblastoma, fibrous tissue and a joint capsule from an arthritic patient.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat ADAMTS5 (NP_942056) VersaClone cDNA - RDC1010 from R&D Systems Prices $499.00 Sizes 10 µg Species Rat

Human ADAMTS5 ORF clone(NM_007038.3) - CDCL182592 from Creative Biomart Species Human Accession NM_007038.3

Human ADAMTS5 ORF Clone(NM_007038.3) - CDCL153145 from Creative Biomart Species Human Accession NM_007038.3

Human ADAMTS5 Gene ORF cDNA clone in cloning vector - HG10423-M from Sino Biological Species Human

Human ADAMTS5 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10423-ACR from Sino Biological Species Human

Human ADAMTS5 Gene cDNA Clone (full-length ORF Clone) expression ready, untagged - HG10423-M-N from Sino Biological Species Human Accession NM_007038.3

Human ADAMTS5 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10423-ACG from Sino Biological Species Human

Human ADAMTS5 Gene ORF cDNA clone expression plasmid, N-His tag - HG10423-NH from Sino Biological Species Human

Human ADAMTS5 Gene ORF cDNA clone expression plasmid - HG10423-UT from Sino Biological Species Human

Human ADAMTS5 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10423-NF from Sino Biological Species Human

Human ADAMTS5 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10423-NM from Sino Biological Species Human

Human ADAMTS5 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10423-CY from Sino Biological Species Human

Human ADAMTS5 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10423-CF from Sino Biological Species Human

Human ADAMTS5 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10423-NY from Sino Biological Species Human

Human ADAMTS5 Gene ORF cDNA clone expression plasmid, C-His tag - HG10423-CH from Sino Biological Species Human

Human ADAMTS5 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10423-CM from Sino Biological Species Human

Human ADAMTS5 ORF clone(NM_007038.3) - CDCL182592 from Creative biogene Species Human

Human ADAMTS5 gene - orb91007 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Mouse ADAMTS5 (NP_035912) VersaClone cDNA - RDC1917 from R&D Systems Prices $499.00 Sizes 10 µg Species Mouse

Human ADAMTS5 (NP_008969) VersaClone cDNA - RDC2148 from R&D Systems Prices $499.00 Sizes 10 µg Species Human

Search more