ADAMTS5

Gene Symbol ADAMTS5
Entrez Gene 11096
Alt Symbol ADAM-TS 11, ADAM-TS 5, ADAM-TS5, ADAMTS-11, ADAMTS-5, ADAMTS11, ADMP-2
Species Human
Gene Type protein-coding
Description ADAM metallopeptidase with thrombospondin type 1 motif, 5
Other Description A disintegrin and metalloproteinase with thrombospondin motifs 5|a disintegrin and metalloproteinase with thrombospondin motifs 11|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)|aggrecanase-2
Swissprots Q9UKP2 Q9UNA0 Q52LV4
Accessions BAA95503 BAA95504 EAX09948 EAX09949 Q9UNA0 AF086299 AF086358 AF141293 AAF02493 AF142099 AAD49577 AK094057 AK095905 BC093775 AAH93775 BC093777 AAH93777 XM_011529448 XP_011527750 NM_007038 NP_008969
Function Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Tissue Specificity Expressed at low level in placenta primarily but also detected in heart and brain, cervix, uterus, bladder, esophagus, rib cartilage, chondroblastoma, fibrous tissue and a joint capsule from an arthritic patient.

ADAMTS-5 CRISPR/Cas9 KO Plasmid (h) - sc-402695 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAMTS-5 HDR Plasmid (h) - sc-402695-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAMTS-5 Double Nickase Plasmid (h) - sc-402695-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAMTS-5 Double Nickase Plasmid (h2) - sc-402695-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAMTS-5 CRISPR Activation Plasmid (h) - sc-402695-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAMTS-5 CRISPR Activation Plasmid (h2) - sc-402695-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAMTS-5 Lentiviral Activation Particles (h) - sc-402695-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAMTS-5 Lentiviral Activation Particles (h2) - sc-402695-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAMTS-5 siRNA (h) - sc-91432 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADAMTS-5 shRNA Plasmid (h) - sc-91432-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADAMTS-5 shRNA (h) Lentiviral Particles - sc-91432-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADAMTS5 RNAi - H00011096-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU121291 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2836 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2836 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ADAMTS5 siRNA (Human) - CRH7588 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADAMTS5 - MBS8200551 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ADAMTS5 (NM_007038.3) - SHH231886 from Creative biogene

Category siRNA
Species Reactivities Human

Human ADAMTS5 siRNA - orb268090 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADAMTS5 shRNA Plasmid (Human) - CHH7588 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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