ADAMTS5

Gene Symbol	ADAMTS5
Entrez Gene	11096
Alt Symbol	ADAM-TS 11, ADAM-TS 5, ADAM-TS5, ADAMTS-11, ADAMTS-5, ADAMTS11, ADMP-2
Species	Human
Gene Type	protein-coding
Description	ADAM metallopeptidase with thrombospondin type 1 motif, 5
Other Description	A disintegrin and metalloproteinase with thrombospondin motifs 5|a disintegrin and metalloproteinase with thrombospondin motifs 11|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)|aggrecanase-2
Swissprots	Q9UKP2 Q9UNA0 Q52LV4
Accessions	BAA95503 BAA95504 EAX09948 EAX09949 Q9UNA0 AF086299 AF086358 AF141293 AAF02493 AF142099 AAD49577 AK094057 AK095905 BC093775 AAH93775 BC093777 AAH93777 XM_011529448 XP_011527750 NM_007038 NP_008969
Function	Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Tissue Specificity	Expressed at low level in placenta primarily but also detected in heart and brain, cervix, uterus, bladder, esophagus, rib cartilage, chondroblastoma, fibrous tissue and a joint capsule from an arthritic patient.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human ADAMTS5 protein fragment - ab134432 from Abcam Category Protein Prices $585.00 Sizes 50 µl Source Baculovirus infected insect cells Species Human

ADAMTS5 peptide - ab41237 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

ADAMTS5 peptide - ab43061 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

ADAMTS5 peptide - ab45238 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

ADAMTS5 peptide - ab50757 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human ADAMTS5 peptide - ab41036 from Abcam Category Peptide

Human ADAMTS5 protein fragment - ab153157 from Abcam Category Protein Source Wheat germ Species Human

ADAMTS5 Antibody Blocking Peptide - LS-E2752 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADAMTS5 Antibody Blocking Peptide - LS-E8962 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADAMTS5 Antibody Blocking Peptide - LS-E28314 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ADAMTS5 Antibody Blocking Peptide - LS-E28313 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ADAMTS5 Antibody Blocking Peptide - LS-E28312 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ADAMTS5 Antibody Blocking Peptide - LS-E28316 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ADAMTS5 Antibody Blocking Peptide - LS-E29283 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ADAMTS5 Antibody Blocking Peptide - LS-E29282 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ADAMTS5 Partial Recombinant Protein - H00011096-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human ADAMTS5 Protein - P4931 from Novus Biologicals Category Protein Prices $799.00 Sizes 5 µg Source insect cells Species Human

ADAMTS5-Antibody-N-term-Blocking-peptide - BP13847a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ADAMTS5-Antibody-Center-Blocking-Peptide - BP7447c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human ADAMTS5, CF - 2198-AD-020 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ser262-Pro622, with a C-terminal 10-His tag

ADAMTS5 - H00011096-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ADAMTS5 - H00011096-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ADAMTS5 - P4931 from Acris Antibodies Category Protein Prices $580.00 Sizes 5 µg Species Human

ADAMTS5 fusion protein - ag12779 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ADAMTS5 fusion protein - ag12780 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

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