PKMYT1

Gene Symbol PKMYT1
Entrez Gene 9088
Alt Symbol MYT1, PPP1R126
Species Human
Gene Type protein-coding
Description protein kinase, membrane associated tyrosine/threonine 1
Other Description membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase|myt1 kinase|protein phosphatase 1, regulatory subunit 126
Swissprots Q99640 F8W164 B4DXD4 O14731 Q8TCM9 I3L1V2 D3DUA4 B3KUN8 Q7LE24
Accessions AAC04477 AAC04478 AAN40703 EAW85439 EAW85440 Q99640 AK097642 BAG53500 AK098452 AK294379 BAG57637 AK301926 BAG63346 AK303005 BAG64138 AK309964 BC121161 AAI21162 BC121162 AAI21163 BC130011 AAI30012 BC153823 BC160025 AAI60025 BG530406 BQ017689 DB009060 DB111506 U56816 AAC50949 XM_011522734 XP_011521036 XM_011522735 XP_011521037 XM_011522736 XP_011521038 NM_001258450 NP_001245379 NM_001258451 NP_001245380 NM_004203 NP_004194 NM_182687 NP_872629
Function Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development. {ECO:0000269|PubMed:10373560, ECO:0000269|PubMed:9001210}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:9001210}; Peripheral membrane protein {ECO:0000269|PubMed:9001210}. Golgi apparatus membrane {ECO:0000269|PubMed:9001210}; Peripheral membrane protein {ECO:0000269|PubMed:9001210}.
Top Pathways Cell cycle, Progesterone-mediated oocyte maturation, Oocyte meiosis

Human PKMYT1 ELISA Kit (Cell-Based ELISA) - LS-F2178 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate

PKMYT1 (Human) IP-WB Antibody Pair - H00009088-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

protein kinase, membrane associated tyrosine/threonine 1, ELISA Kit - MBS9336884 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

MYT1 Colorimetric Cell-Based ELISA Kit - CB5480 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

MYT1 ELISA Kit - DEIA-XYA1300 from Creative Diagnostics

Category ELISA Kit

Human Phospho-PKMYT1 (T495) ELISA - PEL-PKMYT1-T495-1 from RayBiotech

Category ELISA Kit
Prices $481.00, $865.80, $1,924.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human Phospho-PKMYT1 (T495) and Total PKMYT1 ELISA - PEL-PKMYT1-T495-T-1 from RayBiotech

Category ELISA Kit
Prices $525.00, $945.00, $2,100.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human MYT1 ELISA Kit - E025284 from Biobool

Category ELISA Kit

Human PKMYT1 ELISA Kit - E031662 from Biobool

Category ELISA Kit

MYT1 Colorimetric Cell-Based ELISA Kit - EKA50413 from Biomatik

Category ELISA Kit
Prices $399.00
Sizes 96 tests
Sensitivity At least 5000 cells/well
Range Qualitative
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