TARBP2

Gene Symbol TARBP2
Entrez Gene 6895
Alt Symbol LOQS, TRBP, TRBP1, TRBP2
Species Human
Gene Type protein-coding
Description TAR (HIV-1) RNA binding protein 2
Other Description RISC-loading complex subunit TARBP2|TAR (HIV) RNA binding protein 2|TAR (HIV) RNA-binding protein 2|TAR (HIV) RNA-binding protein TRBP1|TAR RNA binding protein 2|TAR RNA-binding protein 2|trans-activation responsive RNA-binding protein|trans-activation-responsive RNA-binding protein
Swissprots Q9BRY2 Q15633 Q8WY33 Q8WY32 Q12878
Accessions AAL55730 AAL55731 EAW96717 EAW96718 EAW96719 EAW96720 Q15633 AK290737 BAF83426 AK293728 BAH11581 AK309569 BC002419 BC005860 AAH05860 BC150583 BI771121 BT007140 AAP35804 DQ893549 ABM84475 DQ893931 ABM84857 M60801 AAA36765 U08998 AAB50581 XM_005269114 XP_005269171 XM_005269115 XP_005269172 XM_005269116 XP_005269173 XM_005269117 XP_005269174 XM_005269120 XP_005269177 XM_005269122 XP_005269179 XM_006719581 XP_006719644 XM_011538712 XP_011537014 XR_944695 NM_004178 NP_004169 NM_134323 NP_599150 NM_134324 NP_599151
Function Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. This is achieved in part at least by binding to and inhibiting EIF2AK2/PKR, thereby reducing phosphorylation and inhibition of EIF2S1/eIF-2-alpha. May also promote translation of TAR-containing RNAs independently of EIF2AK2/PKR. {ECO:0000269|PubMed:12475984, ECO:000
Subcellular Location Cytoplasm. Cytoplasm, perinuclear region. Nucleus.

Human-TARBP2-cDNA-Clone - DC01787 from Abgent, a WuXi AppTec company

Prices $494.10
Sizes 10 µg
Species Human
Accession BC005860

TARBP2 - MBS1274258 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC005860

Human TARBP2 cDNA clone(NM_134323.1) - CDFG007816 from Creative Biomart

Species Human
Accession NM_134323.1

Human TARBP2 cDNA clone(NM_134324.2) - CDFG007818 from Creative Biomart

Species Human
Accession NM_134324.2

Human TARBP2 cDNA clone(NM_004178.4) - CDFH019208 from Creative Biomart

Species Human
Accession NM_004178.4

Human TARBP2 ORF Clone(NM_004178.4) - CDCR287344 from Creative Biomart

Species Human
Accession NM_004178.4

Human TARBP2 ORF Clone(NM_004178.4) - CDCR287345 from Creative Biomart

Species Human
Accession NM_004178.4

Human TARBP2 ORF Clone(NM_134323.1) - CDCR316233 from Creative Biomart

Species Human
Accession NM_134323.1

Human TARBP2 ORF Clone(NM_134323.1) - CDCR316234 from Creative Biomart

Species Human
Accession NM_134323.1

Human TARBP2 ORF Clone(NM_134324.2) - CDCR316235 from Creative Biomart

Species Human
Accession NM_134324.2

Human TARBP2 ORF Clone(NM_134324.2) - CDCR316236 from Creative Biomart

Species Human
Accession NM_134324.2

Human TARBP2 ORF Clone(NM_004178.4) - CDCL177849 from Creative Biomart

Species Human
Accession NM_004178.4

Human TARBP2 ORF Clone(NM_134323.1) - CDCR316233 from Creative biogene

Species Human

Human TARBP2 ORF Clone(NM_134324.2) - CDCR316235 from Creative biogene

Species Human

Mouse TARBP2 ORF clone (NM_004178.4) - CDCL150324 from Creative biogene

Species Human

Human TARBP2 ORF Clone (BC005860) - CDCS411656 from Creative biogene

Species Human
Accession Q15633

Human TARBP2 cDNA Clone(NM_134323.1) - CDFG007816 from Creative biogene

Species Human

Human TARBP2 cDNA Clone(NM_134324.2) - CDFG007818 from Creative biogene

Species Human

Human TARBP2 cDNA Clone(NM_004178.4) - CDFH019208 from Creative biogene

Species Human
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