BABAM1

Gene Symbol	BABAM1
Entrez Gene	29086
Alt Symbol	C19orf62, HSPC142, MERIT40, NBA1
Species	Human
Gene Type	protein-coding
Description	BRISC and BRCA1 A complex member 1
Other Description	BRCA1-A complex subunit MERIT40|BRISC and BRCA1-A complex member 1|mediator of RAP80 interactions and targeting subunit of 40 kDa|mediator of Rap80 interactions and targeting 40 kDa|new component of the BRCA1 A complex|new component of the BRCA1-A complex|new component of the BRCAA1 A complex
Swissprots	Q9P018 Q6FIA0 B4DRY9 B4DVR1 A8MQT0 Q9NWV8
Accessions	EAW84584 EAW84585 Q9NWV8 AF161491 AAF29106 AI948445 AJ572521 AK000578 BAA91268 AK025970 AK225047 AK301193 BAG62773 AK308590 AL136692 CAB66627 AM393637 CAL38513 AM393724 CAL38600 BC000788 AAH00788 BC006244 AAH06244 BC091491 AAH91491 BP246573 CR533526 CAG38557 CX866662 NM_001033549 NP_001028721 NM_001288756 NP_001275685 NM_001288757 NP_001275686 NM_014173 NP_054892
Function	Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36 component. {ECO:0000269|PubMed:19261746, ECO:0000269|PubMed:19261748, ECO:0000269|PubMed:19261749}.
Subcellular Location	Cytoplasm. Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HSPC142 full length protein - ab183249 from Abcam Category Protein Source E. coli Species Human

BABAM1 / HSPC142 Antibody Blocking Peptide - LS-E9649 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BABAM1 / HSPC142 Antibody Blocking Peptide - LS-E9648 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BABAM1 / HSPC142 Antibody Blocking Peptide - LS-E19837 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MERIT40/HSPC142 Recombinant Protein - H00029086-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

HSPC142-Antibody-Center-Blocking-Peptide - BP8573c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HSPC142-Antibody-N-term-Blocking-peptide - BP8573a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BABAM1 protein (His tag) - 80R-3913 from Fitzgerald Category Protein Prices $375.00 Sizes 100 µg Source E.coli

C19ORF62 Blocking Peptide - 33R-2140 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MERIT40 (1-329, His-tag) - AR51600PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 500 µg Source E. coli Species Human

MERIT40 (1-329, His-tag) - AR51600PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

MERIT40 - H00029086-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MERIT40 - H00029086-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

C19orf62 fusion protein - ag13849 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

C19orf62 fusion protein - ag14878 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human BABAM1, His-tagged - BABAM1-29407TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Chromosome 19 Open Reading Frame 62, His-tagged - C19orf62-2924H from Creative Biomart Category Protein Source E.coli.

Recombinant Human BRISC and BRCA1-A complex member 1(BABAM1) - CSB-YP885748HU CSB-EP885748HU CSB-BP885748HU CSB-MP885748HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Pongo abelii BRISC and BRCA1-A complex member 1(BABAM1) - CSB-YP716084PYX CSB-EP716084PYX CSB-BP716084PYX CSB-MP716084PYX from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Orangutan

Recombinant Callithrix jacchus BRISC and BRCA1-A complex member 1(BABAM1) - CSB-YP003477CYL CSB-EP003477CYL CSB-BP003477CYL CSB-MP003477CYL from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell

BABAM1, 1-329aa, Human, His tag, E.coli - ATGP2780 from ATGen Category Protein Prices $105.00, $320.00, $960.00 Sizes 20 µg, 100 µg, 500 µg Species Human

MERIT40 (transcript variant 2) - TP302644 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MERIT40 (transcript variant 1) - TP310626 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

BRISC And BRCA1 A Complex Member 1 Protein (Recombinant) - abx261967 from Abbexa Category Protein

MERIT40/HSPC142 Recombinant Protein Antigen - NBP2-49568PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

Search more