Gene Symbol | SLC43A1 |
---|---|
Entrez Gene | 8501 |
Alt Symbol | LAT3, PB39, POV1, R00504 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 43 (amino acid system L transporter), member 1 |
Other Description | L-type amino acid transporter 3|large neutral amino acids transporter small subunit 3|prostate cancer overexpressed gene 1 protein|solute carrier family 43, member 1 |
Swissprots | O75387 |
Accessions | EAW73749 EAW73750 EAW73751 EAW73752 O75387 AA040589 AB103033 BAD00152 AF045584 AAC33004 AK027732 BAG51373 BC001639 AAH01639 BM147085 BQ029981 XM_005274358 XP_005274415 XM_011545320 XP_011543622 XM_011545321 XP_011543623 XM_011545322 XP_011543624 XM_011545323 XP_011543625 XR_950084 NM_001198810 NP_001185739 NM_003627 NP_003618 |
Function | Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer. {ECO:0000269|PubMed:11956097, ECO:0000269|PubMed:12930836, ECO:0000269|PubMed:9255310, ECO:0000269|PubMed:9722952}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells. {ECO:0000269|PubMed:11956097, ECO:0000269|PubMed:12930836, ECO:0000269|PubMed:9255310, ECO:0000269|PubMed:9722952}. |
SLC43A1 (V-12) - sc-138617 from Santa Cruz Biotechnology
|
||||||||
Anti-LAT3 antibody - ab70177 from Abcam
|
||||||||
Anti-SLC43A1 Antibody (aa275-320) - LS-C313954 from LifeSpan Bioscience
|
||||||||
Anti-SLC43A1 Antibody (aa231-280) - LS-C118707 from LifeSpan Bioscience
|
||||||||
Anti-SLC43A1 Antibody (aa324-373) - LS-C110829 from LifeSpan Bioscience
|
||||||||
LAT3 Antibody - NBP1-87331 from Novus Biologicals
|
||||||||
LAT3 Antibody - NBP1-59431 from Novus Biologicals
|
||||||||
LAT3 Antibody - NBP1-87332 from Novus Biologicals
|
||||||||
Anti-SLC43A1 antibody produced in rabbit - SAB2102216 from Sigma-Aldrich
|
||||||||
Anti-LAT3 antibody produced in rabbit - SAB4503399 from Sigma-Aldrich
|
||||||||
Anti-SLC43A1 antibody produced in rabbit - HPA018826 from Sigma-Aldrich
|
||||||||
Anti-SLC43A1 antibody produced in rabbit - HPA018813 from Sigma-Aldrich
|
||||||||
SLC43A1 antibody - middle region (ARP43854_P050) - ARP43854_P050 from Aviva Systems Biology
|
||||||||
LAT3 antibody - GTX87751 from GeneTex
|
||||||||
SLC43A1 Antibody (OAAF02051) - OAAF02051 from Aviva Systems Biology
|
||||||||
SLC43A1 antibody - 70R-20356 from Fitzgerald
|
||||||||
LAT3 antibody - 70R-33735 from Fitzgerald
|
||||||||
SLC43A1 antibody - 70R-6331 from Fitzgerald
|
||||||||
LAT3 Antibody - abx013318 from Abbexa
|
||||||||
SLC43A1 Antibody - abx008522 from Abbexa
|
||||||||
SLC43A1 / LAT3 antibody - 10444-1-AP from Acris Antibodies
|
||||||||
Anti-SLC43A1 antibody - STJ95680 from St John's Laboratory Ltd
|
||||||||
SLC43A1 antibody - 10444-1-AP from Proteintech Group
|
||||||||
LAT3 Polyclonal Antibody - PA002190-C10170 from Syd Labs
|
||||||||
LAT3 Antibody - 33609 from Signalway Antibody
|