Gene Symbol | SLC43A1 |
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Entrez Gene | 8501 |
Alt Symbol | LAT3, PB39, POV1, R00504 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 43 (amino acid system L transporter), member 1 |
Other Description | L-type amino acid transporter 3|large neutral amino acids transporter small subunit 3|prostate cancer overexpressed gene 1 protein|solute carrier family 43, member 1 |
Swissprots | O75387 |
Accessions | EAW73749 EAW73750 EAW73751 EAW73752 O75387 AA040589 AB103033 BAD00152 AF045584 AAC33004 AK027732 BAG51373 BC001639 AAH01639 BM147085 BQ029981 XM_005274358 XP_005274415 XM_011545320 XP_011543622 XM_011545321 XP_011543623 XM_011545322 XP_011543624 XM_011545323 XP_011543625 XR_950084 NM_001198810 NP_001185739 NM_003627 NP_003618 |
Function | Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer. {ECO:0000269|PubMed:11956097, ECO:0000269|PubMed:12930836, ECO:0000269|PubMed:9255310, ECO:0000269|PubMed:9722952}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells. {ECO:0000269|PubMed:11956097, ECO:0000269|PubMed:12930836, ECO:0000269|PubMed:9255310, ECO:0000269|PubMed:9722952}. |
Human LAT3 full length protein - ab160056 from Abcam
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Human LAT3 protein fragment - ab160057 from Abcam
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SLC43A1 Antibody Blocking Peptide - LS-E16123 from LifeSpan Bioscience
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LAT3 Partial Recombinant Protein - H00008501-Q01 from Novus Biologicals
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Recombinant Human LAT3 Protein - H00008501-P01 from Novus Biologicals
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SLC43A1-Antibody-Center-Blocking-Peptide - BP17606c from Abgent, a WuXi AppTec company
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Recombinant human Large neutral amino acids transporter small subunit 3 (OPCA00988) - OPCA00988 from Aviva Systems Biology
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Human SLC43A1 protein - orb245556 from Biorbyt
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SLC43A1 Blocking Peptide - 33R-1608 from Fitzgerald
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SLC43A1 Blocking Peptide - abx063479 from Abbexa
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SLC43A1 / LAT3 - H00008501-P01-10 from Acris Antibodies
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SLC43A1 / LAT3 - H00008501-P01-25 from Acris Antibodies
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SLC43A1 / LAT3 - H00008501-Q01-10 from Acris Antibodies
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SLC43A1 / LAT3 - H00008501-Q01-25 from Acris Antibodies
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SLC43A1 fusion protein - ag0305 from Proteintech Group
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SLC43A1 Blocking Peptide - CBP2285 from Cohesion Biosciences
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SLC43A1 Peptide - BS5933P from Bioworld Technology
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Recombinant human Large neutral amino acids transporter small subunit 3 - CSB-EP133474h CSB-BP133474h CSB-MP133474h from Cusabio
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Recombinant Human Large neutral amino acids transporter small subunit 3(SLC43A1),partial - CSB-RP133474h from Cusabio
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Large neutral amino acids transporter small subunit 3 - RPC140802 from Biomatik
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LAT3 Recombinant Protein Antigen - NBP1-87331PEP from Novus Biologicals
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LAT3 Recombinant Protein Antigen - NBP1-87332PEP from Novus Biologicals
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SLC43A1 Peptide, Human - M34GP14577H from Creative Peptides
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Recombinant human Large neutral amino acids transporter small subunit 3 - AP72213 from Signalway Antibody
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Large neutral amino acids transporter small subunit 3, Recombinant Protein - MBS9421967 from MyBioSource
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