ALKBH1

Gene Symbol ALKBH1
Entrez Gene 8846
Alt Symbol ABH, ABH1, ALKBH, alkB, hABH
Species Human
Gene Type protein-coding
Description alkB, alkylation repair homolog 1 (E. coli)
Other Description DNA lyase ABH1|DNA oxidative demethylase ALKBH1|alkylated DNA repair protein alkB homolog 1|alkylation repair, alkB homolog|alpha-ketoglutarate-dependent dioxygenase ABH1
Swissprots Q9ULA7 Q13686 Q8TAU1
Accessions AAF01478 EAW81300 EAW81301 EAW81302 Q13686 BC015024 AAH15024 BC025787 AAH25787 BX537699 DQ890543 ABM92160 DQ893703 ABM84629 X91992 CAA63047 XM_005268165 XP_005268222 NM_006020 NP_006011 NM_001039506
Function Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation (By similarity). Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron. {ECO:0000250, ECO:0000269|PubMed:18603530, ECO:0000269|PubMed:19959401}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:17979886, ECO:0000269|PubMed:18603530}. Nucleus {ECO:0000250}. Note=Mainly localizes in euchromatin, largely excluded from heterochromatin and nucleoli. {ECO:0000250}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:17979886, ECO:0000269|PubMed:18603530}.

ALKB (C-20) - sc-48121 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ALKB (F-4) - sc-374301 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ALKB (F-4): sc-374301. Western blot analysis of ALKB expression in Jurkat whole cell lysate.

ALKB (H-300) - sc-67186 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-ABH1 antibody - ab169689 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-ABH1 antibody (ab169689) at 1 µg/mlLane 1 : ABH1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-ABH1 antibody - ab113507 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ABH1 antibody (ab113507) at 1/1000 dilutionLane 1 : Human fetal brain lysateLane 2 : Human fetal lung lysateLane 3 : Human fetal kidney lysate

Anti-ABH1 antibody - ab97589 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-ABH1 antibody (ab97589) at 1/1000 dilution + NT2D1 whole cell lysate at 30 µg

Anti-ABH1 antibody - ab88775 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-ABH1 antibody (ab88775) at 1/500 dilution + Jurkat cell lysate at 50 µg

Anti-ABH1 antibody [EPR6175(2)] - ab128895 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6175(2)
All lanes : Anti-ABH1 antibody [EPR6175(2)] (ab128895) at 1/1000 dilutionLane 1 : A431 cell lysateLane 2 : Jurkat cell lysateLane 3 : A549 cell lysateLane 4 : K562 cell lysateLane 5 : Raw 264.7 cell lysateLane 6 : NIH3T3 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-ABH1 antibody [EPR6176] - ab126596 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6176
All lanes : Anti-ABH1 antibody [EPR6176] (ab126596) at 1/1000 dilutionLane 1 : Jurkat cell lysateLane 2 : K562 cell lysateLane 3 : A549 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-ABH1 antibody [hABH1-151] - ab49738 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone hABH1-151

Anti-ABH1 antibody - N-terminal - ab166726 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-ABH1 antibody - N-terminal (ab166726) at 1/1000 dilutionLane 1 : Mouse brain total cell extractLane 2 : Mouse thymus total cell extractLane 3 : HeLa total cell extractLane 4 : Jurkat total cell extract

Anti-ALKBH1 / ALKB Antibody (aa8-216) - LS-C178535 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALKBH1 / ALKB Antibody - LS-C341990 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALKBH1 / ALKB Antibody (aa97-146) - LS-C145568 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ALKBH1 / ALKBH antibody LS-C145568 Western blot of Fetal Kidney lysate. Antibody concentration 1 ug/ml.

Anti-ALKBH1 / ALKB Antibody (aa166-387) - LS-C186395 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: NT2D1. 10% SDS PAGE. ALKBH1 / ALKB antibody diluted at 1:1000.

Anti-ALKBH1 / ALKB Antibody - LS-C334580 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using ALKBH1 antibody.

Anti-ALKBH1 / ALKB Antibody (aa1-245, clone 1B8) - LS-C339690 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B8
IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ALKBH1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-ALKBH1 / ALKB Antibody (Internal, clone EPR6176) - LS-C152279 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6176
IHC of paraffin-embedded human kidney tissue using anti-ALKBH antibody.

Anti-ALKBH1 / ALKB Antibody (aa1-245, clone 4C4) - LS-C339667 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4C4
IHC of paraffin-embedded Human tonsil using anti-ALKBH1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-ALKBH1 / ALKB Antibody (N-Terminus, clone EPR6175(2)) - LS-C152427 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6175(2)
IHC of paraffin-embedded human breast carcinoma tissue using anti-ALKBH antibody.

ABH1 Antibody - NBP2-14283 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ABH1 Antibody [NBP2-14283] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4

ABH1 Antibody - NBP1-79909 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ABH1 Antibody [NBP1-79909] - Human Fetal Kidney Lysate 1ug/ml  Gel Concentration 12%

ABH1 Antibody - H00008846-B02 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: ABH1 Antibody [H00008846-B02] - ALKBH1 MaxPab polyclonal antibody. Western Blot analysis of ALKBH1 expression in Jurkat.

ABH1 Antibody - H00008846-B01P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

ABH1/ALKB Polyclonal Antibody - bs-12565R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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