Gene Symbol | AKAP5 |
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Entrez Gene | 9495 |
Alt Symbol | AKAP75, AKAP79, H21 |
Species | Human |
Gene Type | protein-coding |
Description | A kinase (PRKA) anchor protein 5 |
Other Description | A-kinase anchor protein 5|A-kinase anchor protein 79 kDa|A-kinase anchoring protein 75/79|AKAP 79|cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein |
Swissprots | P24588 A2RRB8 |
Accessions | EAW80862 P24588 AK124004 AK315336 BAG37736 BC057229 AAH57229 BC131516 AAI31517 DA942424 M90359 AAA58363 NM_004857 NP_004848 |
Function | May anchor the PKA protein to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors. Association with to the beta2-adrenergic receptor (beta2-AR) not only regulates beta2-AR signaling pathway, but also the activation by PKA by switching off the beta2-AR signaling cascade. |
Subcellular Location | Membrane {ECO:0000269|PubMed:21771783}; Lipid-anchor {ECO:0000269|PubMed:21771783}. Note=Associates with lipid rafts. |
Tissue Specificity | Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary. |
AKAP5 (D28G3) Rabbit mAb - 5671 from Cell Signaling Technology
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AKAP 79 (D-9) - sc-17772 from Santa Cruz Biotechnology
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AKAP 79 (H-105) - sc-10764 from Santa Cruz Biotechnology
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AKAP 79 (N-19) - sc-6442 from Santa Cruz Biotechnology
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AKAP 79 (22) - sc-135826 from Santa Cruz Biotechnology
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Anti-AKAP5 antibody - ab64851 from Abcam
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Anti-AKAP5 antibody - ab138942 from Abcam
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Anti-AKAP5 antibody - ab85439 from Abcam
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Anti-E. coli H-21 antibody - ab79136 from Abcam
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Anti-AKAP5 / AKAP79 Antibody (aa428-449) - LS-C34917 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (Glu7) - LS-C191954 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (aa115-143, AP) - LS-C251084 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (aa115-143, APC) - LS-C251086 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (aa115-143, Biotin) - LS-C251087 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (aa115-143, FITC) - LS-C251088 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (aa115-143, Azide-free, HRP) - LS-C251089 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (aa115-143, PE) - LS-C251090 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (C-Terminus) - LS-C101623 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (aa334-427) - LS-C306171 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody - LS-C178486 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (aa115-143) - LS-C161025 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (aa114-143) - LS-C319393 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody - LS-C346107 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (aa171-417) - LS-C178647 from LifeSpan Bioscience
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Anti-AKAP5 / AKAP79 Antibody (aa1-50) - LS-C118834 from LifeSpan Bioscience
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