Gene Symbol | AKAP5 |
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Entrez Gene | 9495 |
Alt Symbol | AKAP75, AKAP79, H21 |
Species | Human |
Gene Type | protein-coding |
Description | A kinase (PRKA) anchor protein 5 |
Other Description | A-kinase anchor protein 5|A-kinase anchor protein 79 kDa|A-kinase anchoring protein 75/79|AKAP 79|cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein |
Swissprots | P24588 A2RRB8 |
Accessions | EAW80862 P24588 AK124004 AK315336 BAG37736 BC057229 AAH57229 BC131516 AAI31517 DA942424 M90359 AAA58363 NM_004857 NP_004848 |
Function | May anchor the PKA protein to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors. Association with to the beta2-adrenergic receptor (beta2-AR) not only regulates beta2-AR signaling pathway, but also the activation by PKA by switching off the beta2-AR signaling cascade. |
Subcellular Location | Membrane {ECO:0000269|PubMed:21771783}; Lipid-anchor {ECO:0000269|PubMed:21771783}. Note=Associates with lipid rafts. |
Tissue Specificity | Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary. |
AKAP5 protein (His-DHFR tag) - ab127463 from Abcam
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Human AKAP5 full length protein - ab132675 from Abcam
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AKAP5 / AKAP79 Antibody Blocking Peptide - LS-E6430 from LifeSpan Bioscience
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AKAP5 / AKAP79 Antibody Blocking Peptide - LS-E13003 from LifeSpan Bioscience
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Recombinant Human AKAP5 Protein - H00009495-P01 from Novus Biologicals
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Recombinant Human AKAP5 Protein - H00009495-Q01 from Novus Biologicals
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AKAP5-Antibody-Center-Blocking-Peptide - BP19171c from Abgent, a WuXi AppTec company
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AKAP5 Blocking Peptide - 33R-4603 from Fitzgerald
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AKAP5 - H00009495-P01-10 from Acris Antibodies
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AKAP5 - H00009495-P01-25 from Acris Antibodies
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AKAP5 - H00009495-Q01-10 from Acris Antibodies
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AKAP5 - H00009495-Q01-25 from Acris Antibodies
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AKAP5 fusion protein - ag19162 from Proteintech Group
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Recombinant Human AKAP5, His-tagged - AKAP5-23H from Creative Biomart
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Recombinant Human AKAP5, His-tagged - AKAP5-3030H from Creative Biomart
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Recombinant Human AKAP5 - AKAP5-714H from Creative Biomart
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AKAP5 Blocking Peptide - CBP3367 from Cohesion Biosciences
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AKAP 5 (E7) Peptide - BS1962P from Bioworld Technology
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Recombinant Human A-kinase anchor protein 5(AKAP5) - CSB-YP001527HU CSB-EP001527HU CSB-BP001527HU CSB-MP001527HU from Cusabio
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A-kinase anchor protein 5 (AKAP5) - MBS1256523 from MyBioSource
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AKAP5 Blocking Peptide - abx162229 from Abbexa
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AKAP5 Peptide, Human - M34GP00440H from Creative Peptides
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AKAP5 Recombinant Protein Antigen - NBP2-38713PEP from Novus Biologicals
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SH3 domain scaffold protein anti-Human AKAP79 - SST-L187 from Creative Biolabs
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AKAP5 Peptide - orb224253 from Biorbyt
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