RRAD

Gene Symbol RRAD
Entrez Gene 6236
Alt Symbol RAD, RAD1, REM3
Species Human
Gene Type protein-coding
Description Ras-related associated with diabetes
Other Description GTP-binding protein RAD|RAS (RAD and GEM) like GTP binding 3|ras associated with diabetes
Swissprots Q96F39 P55042
Accessions AAB17064 EAW83053 EAW83054 EAW83055 P55042 AK290613 BAF83302 BC011645 AAH11645 BC057815 AAH57815 BP257026 DQ891951 ABM82877 DQ895137 ABM86063 L24564 AAA36540 N93445 NM_001128850 NP_001122322 NM_004165 NP_004156
Function May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha- 1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D. {ECO:0000250, ECO:0000269|PubMed:18056528}.
Subcellular Location Cell membrane {ECO:0000250}.
Tissue Specificity Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans. {ECO:0000269|PubMed:18056528}.

Rad GTPase (B-10) - sc-373988 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rad GTPase (B-10): sc-373988. Western blot analysis of Rad GTPase expression in NCI-H1688 whole cell lysate.

Rad GTPase (H-143) - sc-134823 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rad GTPase (H-143): sc-134823. Western blot analysis of Rad GTPase expression in NCI-H1688 whole cell lysate.

Rad GTPase (K-16) - sc-49716 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Rad GTPase (D-15) - sc-49714 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Rad GTPase (D-15): sc-49714. Western blot analysis of Rad GTPase expression in A-673 (A) and SJRH30 (B) whole cell lysates.

Anti-RRAD antibody - ab75100 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RRAD antibody (ab75100) at 1/500 dilutionLane 1 : Extracts from HeLa cellsLane 2 : Extracts from HepG2 cells Lane 3 : Extracts from MCF-7 cellsLane 4 : Extracts from HeLa cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-RRAD antibody [EPR12856] - ab177151 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12856
All lanes : Anti-RRAD antibody [EPR12856] (ab177151) at 1/1000 dilutionLane 1 : Human fetal heart lysateLane 2 : Human fetal lung lysateLane 3 : A673 lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-RRAD Antibody (aa143-192) - LS-C107586 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RRAD antibody LS-C107586 Western blot of MCF7 cell lysate.

Anti-RRAD Antibody (aa36-48) - LS-C154980 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
RRAD antibody a): (0.5 ug/ml) staining of HEK293 lysates overexpressing several HA-tagged Mouse GTPases, including Rrad (10 ug protein in RIPA buffer) and compared with an HA-specific antibody. B): (0.5 ug/ml) staining of WT and KO lysates of Mouse Heart (100 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-RRAD Antibody (Leu80) - LS-C177379 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of Rad GTPase (L80) pAb in paraffin-embedded human heart tissue.

Anti-RRAD Antibody (aa41-90) - LS-C120027 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human heart tissue, using RAD Antibody. The picture on the right is treated with the synthesized peptide.

Anti-RRAD Antibody (aa107-156) IHC-plus™ - LS-B11529 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)

RRAD Antibody - NBP1-58864 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RRAD Antibody [NBP1-58864] - Sample Type: Human Adult Placenta Antibody Dilution: 1.0 ug/ml

RRAD Antibody - NBP2-13266 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: RRAD Antibody [NBP2-13266] - Staining of human cell line A549 shows localization to nucleoplasm, plasma membrane & the Golgi apparatus.

RRAD Antibody - NBP2-27500 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

RRAD Polyclonal Antibody - bs-0278R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RRAD Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0278R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RRAD Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0278R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RRAD Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0278R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RRAD Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0278R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RRAD Polyclonal Antibody, Cy3 Conjugated - bs-0278R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RRAD Polyclonal Antibody, Cy5 Conjugated - bs-0278R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RRAD Polyclonal Antibody, Cy5.5 Conjugated - bs-0278R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RRAD Polyclonal Antibody, Cy7 Conjugated - bs-0278R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RRAD Polyclonal Antibody, FITC Conjugated - bs-0278R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RRAD Polyclonal Antibody, Biotin Conjugated - bs-0278R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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