MAP3K13

Gene Symbol	MAP3K13
Entrez Gene	9175
Alt Symbol	LZK, MEKK13, MLK
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase kinase kinase 13
Other Description	leucine zipper-bearing kinase|mixed lineage kinase
Swissprots	Q15450 Q05BY6 B4DLE3 O43283 B4DMV2 D3DNU1 B4DZJ4 B2R6U2 Q2NKN3
Accessions	EAW78224 EAW78225 O43283 AB001872 BAA24817 AI690808 AK123148 AK296961 BAG59505 AK297646 BAG60014 AK302951 BAG64106 AK312714 BAG35589 BC015996 BC026249 BC031677 AAH31677 BC036593 BC111726 AAI11727 BQ432918 Z25428 CAA80915 XM_011513310 XP_011511612 NM_001242314 NP_001229243 NM_001242317 NP_001229246 NR_038322 NM_004721 NP_004712
Function	Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B. {ECO:0000269|PubMed:11726277, ECO:0000269|PubMed:12492477, ECO:0000269|PubMed:9353328}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9353328}. Membrane {ECO:0000269|PubMed:9353328}; Peripheral membrane protein {ECO:0000269|PubMed:9353328}.
Tissue Specificity	Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas. {ECO:0000269|PubMed:9353328}.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MAP3K13 full length protein - ab160368 from Abcam Category Protein Source Wheat germ Species Human

Human MAP3K13 protein fragment - ab160369 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human MAP3K13 Protein - H00009175-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MAP3K13 Partial Recombinant Protein - H00009175-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MAP3K13 peptide - orb218229 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Cat

LZK Blocking Peptide - abx063560 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Dog, Rabbit

MAP3K13 - H00009175-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MAP3K13 - H00009175-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MAP3K13 - H00009175-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MAP3K13 - H00009175-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MAP3K13 - P5582 from Acris Antibodies Category Protein Prices $1,010.00 Sizes 5 µg Species Human

LZK Blocking Peptide - CBP2366 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Chicken, Dog, Rabbit

LZK (F183) Peptide - BS1874P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Mitogen-activated protein kinase kinase kinase 13(MAP3K13) ,partial - CSB-YP013421HU CSB-EP013421HU CSB-BP013421HU CSB-MP013421HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MAP3K13 Recombinant Protein Antigen - NBP1-81274PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MAP3K13 Recombinant Protein Antigen - NBP1-81273PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MAP3K13 Recombinant Protein Antigen - NBP1-81272PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MAP3K13-LZK-Antibody-C-term-Blocking-peptide - BP8008a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAP3K13-LZK-Blocking-Peptide-C-term-S869 - BP8008d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAP3K13 Peptide, Human - M34GP09169H from Creative Peptides Category Peptide Source Synthetic. Species Human

MAP3K13 fusion protein - Ag26907 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Mitogen-activated protein kinase kinase kinase 13 (MAP3K13), partial, Recombinant Protein - MBS1153016 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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