ACVRL1

Gene Symbol	ACVRL1
Entrez Gene	94
Alt Symbol	ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Species	Human
Gene Type	protein-coding
Description	activin A receptor type II-like 1
Other Description	TGF-B superfamily receptor type I|activin A receptor, type II-like kinase 1|serine/threonine-protein kinase receptor R3
Swissprots	P37023 A6NGA8
Accessions	AAB61900 CAA02404 EAW58211 EAW58212 EAW58213 EAW58214 P37023 AK056725 AK298493 BAG60701 AK300619 BAG62312 AK303331 BAG64396 BC042637 AAH42637 DN999570 HM161905 ADJ79922 HM161906 ADJ79923 JF432428 ADZ15645 L17075 AAA16160 Z22533 CAA80255 XM_005269235 XP_005269292 XM_011539008 XP_011537310 NM_000020 NP_000011 NM_001077401 NP_001070869
Function	Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. {ECO:0000269|PubMed:22718755, ECO:0000269|PubMed:22799562}.
Subcellular Location	Membrane; Single-pass type I membrane protein.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human ACVRL1 protein fragment - ab70317 from Abcam Category Protein Prices $302.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

ACVRL1 peptide - ab190772 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human ACVRL1 full length protein - ab132046 from Abcam Category Protein Source Wheat germ Species Human

Human ACVRL1 peptide - ab86637 from Abcam Category Peptide

Human ACVRL1 peptide - ab23196 from Abcam Category Peptide Species Human

Human ACVRL1 protein fragment - ab152168 from Abcam Category Protein Source Wheat germ Species Human

Human ACVRL1 protein fragment - ab151877 from Abcam Category Protein Source HEK 293 cells Species Human

ACVRL1 Antibody Blocking Peptide - LS-E25679 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACVRL1 Antibody Blocking Peptide - LS-E16239 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACVRL1 Antibody Blocking Peptide - LS-E9277 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACVRL1 Antibody Blocking Peptide - LS-E9278 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ALK-1 Recombinant Protein - H00000094-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ALK-1 Partial Recombinant Protein - H00000094-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ALK-1 Peptide - P2812 from Novus Biologicals Category Peptide Species Human

ALK-1 Peptide - P2811 from Novus Biologicals Category Peptide Species Human

ACVRL1-Antibody-C-term-Blocking-Peptide - BP7807b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ACVRL1-Antibody-N-term-Blocking-Peptide - BP7807a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ACVRL1 blocking peptide - GTX10179-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human ALK-1 Fc Chimera, CF - 370-AL-100 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human ALK 1 protein - orb84728 from Biorbyt Category Protein Prices $323.00, $434.00 Sizes 100 μg, 200 μg Source Insect Species Human

Canine ALK-1 protein - orb138155 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 100 μg, 200 μg Source Human Cells

ACVRL1 Immunizing peptide - orb17855 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

ACVRL1 Blocking Peptide - 33R-8676 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ACVRL1 Peptide - AC21-0509-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ACVRL1 / ALK1 - H00000094-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

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