F2R

Gene Symbol F2R
Entrez Gene 2149
Alt Symbol CF2R, HTR, PAR-1, PAR1, TR
Species Human
Gene Type protein-coding
Description coagulation factor II (thrombin) receptor
Other Description protease-activated receptor 1|proteinase-activated receptor 1
Swissprots Q9BUN4 Q96RF7 P25116 Q53XV0
Accessions AAC25993 AAC50740 AAK69768 EAW95779 EAW95780 EAW95781 P25116 AK297131 BAG59635 AK308169 AK314202 AY771596 AAX11426 BC002464 AAH02464 BC016059 BC051909 AAH51909 BT007279 AAP35943 DQ895099 ABM86025 EU176315 ABW03766 M62424 AAA36743 S76625 AAD14229 NM_001992 NP_001983
Function High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development. {ECO:0000269|PubMed:10079109}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Platelets and vascular endothelial cells.
Top Pathways Rap1 signaling pathway, cAMP signaling pathway, PI3K-Akt signaling pathway, Endocytosis, Calcium signaling pathway

Thrombin R (ATAP2) - sc-13503 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Thrombin R (ATAP2): sc-13503. Immunofluorescence staining of methanol-fixed KNRK cells showing cytoplasmic localization using indirect FITC (A) staining and HeLa cells using direct Alexa Fluor 488 (B) staining.

Thrombin R (C-11) - sc-271100 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Thrombin R (C-11): sc-271100. Western blot analysis of Thrombin R recombinant fusion protein.

Thrombin R (C-18) - sc-8202 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Thrombin R (C-18): sc-8202. Immunofluorescence staining of methanol-fixed Hep G2 cells showing membrane localization.

Thrombin R (G-7) - sc-133128 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Thrombin R (G-7): sc-133128. Western blot analysis of Thrombin R expression in non-transfected: sc-117752 (A) and human Thrombin R transfected: sc-116387 (B) 293T whole cell lysates.

Thrombin R (N-19) - sc-8203 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Thrombin R (N-19): sc-8203. Western blot analysis of human recombinant Thrombin R fusion protein.

Thrombin R (H-111) - sc-5605 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Thrombin R (H-111): sc-5605. Western blot analysis of Thrombin R expression in KNRK whole cell lysate.

Anti-Thrombin Receptor antibody - ab32611 from Abcam

Prices $382.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
This image shows human pancreas stained with ab32611.

Anti-Thrombin Receptor antibody - ab183083 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue labeling Thrombin Receptor with ab183083 at 1/40 dilution. The image on the right is treated with the immunizing peptide.

Anti-Thrombin Receptor antibody - ab117749 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Thrombin Receptor antibody (ab117749) at 1 µg/ml + Platelet (Human) Whole Cell Lysate at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Thrombin Receptor antibody - ab63445 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Thrombin Receptor antibody (ab63445) at 1/500 dilutionLane 1 : HeLa cell extracts treated with Nocodazole (1ug/ml, 18hours)Lane 2 : HeLa cell extracts treated with Nocodazole (1ug/ml, 18hours) with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-Thrombin Receptor antibody - ab111976 from Abcam

Prices $378.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab111976, at 2.5µg/ml, staining Thrombin Receptor in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry.

Anti-Thrombin Receptor antibody - ab87647 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Thrombin Receptor antibody (ab87647) at 0.5 µg/ml + HeLa cell lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-Thrombin Receptor antibody [MM0859-11U34] - ab201655 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0859-11U34

Anti-Thrombin Receptor antibody, prediluted - ab32612 from Abcam

Prices $376.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
Ab32012, prediluted, staining Thrombin Receptor in formalin fixed paraffin embedded human pancreas tissue sections by Immunohistochemistry.

Anti-F2R / Thrombin Receptor / PAR1 Antibody (aa27-102) - LS-C38063 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-F2R / Thrombin Receptor / PAR1 Antibody (aa1-425) - LS-C131210 from LifeSpan Bioscience

Prices $445.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-F2R / Thrombin Receptor / PAR1 Antibody (N-Terminus) - LS-C144917 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-F2R / Thrombin Receptor / PAR1 Antibody (clone N2-11, DY650) - LS-C180674 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone N2-11

Anti-F2R / Thrombin Receptor / PAR1 Antibody (clone N2-11, Biotin) - LS-C180673 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone N2-11

Anti-F2R / Thrombin Receptor / PAR1 Antibody (Ser42) - LS-C178240 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Thrombin R (S42) pAb in extracts from HeLa cells.

Anti-F2R / Thrombin Receptor / PAR1 Antibody (clone N2-11, DY488) - LS-C180675 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone N2-11

Anti-F2R / Thrombin Receptor / PAR1 Antibody (clone N2-11, HRP) - LS-C180676 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone N2-11

Anti-F2R / Thrombin Receptor / PAR1 Antibody (aa51-100) - LS-C111321 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
F2R / Thrombin Receptor antibody LS-C111321 Western blot of HeLa lysate.

Anti-F2R / Thrombin Receptor / PAR1 Antibody (Gly17) - LS-C176689 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of PAR1 (G17) pAb in extracts from HeLa cells treated with Nocodazole 1 ug/ml 18 hours.

Anti-F2R / Thrombin Receptor / PAR1 Antibody (aa10-59) - LS-C118592 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HeLa cells, treated with Nocodazole 1 ug/ml 18h, using Thrombin Receptor Antibody. The lane on the right is treated with the synthesized peptide.
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