F2R

Gene Symbol	F2R
Entrez Gene	2149
Alt Symbol	CF2R, HTR, PAR-1, PAR1, TR
Species	Human
Gene Type	protein-coding
Description	coagulation factor II (thrombin) receptor
Other Description	protease-activated receptor 1|proteinase-activated receptor 1
Swissprots	Q9BUN4 Q96RF7 P25116 Q53XV0
Accessions	AAC25993 AAC50740 AAK69768 EAW95779 EAW95780 EAW95781 P25116 AK297131 BAG59635 AK308169 AK314202 AY771596 AAX11426 BC002464 AAH02464 BC016059 BC051909 AAH51909 BT007279 AAP35943 DQ895099 ABM86025 EU176315 ABW03766 M62424 AAA36743 S76625 AAD14229 NM_001992 NP_001983
Function	High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development. {ECO:0000269|PubMed:10079109}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Platelets and vascular endothelial cells.
Top Pathways	Rap1 signaling pathway, cAMP signaling pathway, PI3K-Akt signaling pathway, Endocytosis, Calcium signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Thrombin R CRISPR/Cas9 KO Plasmid (h) - sc-400556 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Thrombin R HDR Plasmid (h) - sc-400556-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Thrombin R Double Nickase Plasmid (h) - sc-400556-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Thrombin R Double Nickase Plasmid (h2) - sc-400556-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Thrombin R CRISPR Activation Plasmid (h) - sc-400556-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Thrombin R CRISPR Activation Plasmid (h2) - sc-400556-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Thrombin R Lentiviral Activation Particles (h) - sc-400556-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Thrombin R Lentiviral Activation Particles (h2) - sc-400556-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Thrombin R siRNA (h) - sc-36663 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Thrombin R shRNA Plasmid (h) - sc-36663-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Thrombin R shRNA (h) Lentiviral Particles - sc-36663-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PAR1/Thrombin Receptor RNAi - H00002149-R02 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU000271 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1128 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1127 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1127 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1128 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

F2R siRNA (Human) - CRH1493 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

F2R - MBS8206703 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human F2R (NM_001992.3) - SHH288441 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human F2R(NM_001992.3) - SHH043463 from Creative biogene Category siRNA Species Reactivities Human

Human F2R siRNA - orb261995 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

F2R shRNA Plasmid (Human) - CHH1493 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

F2R miRNA 3'UTR clone - MiUTR1H-03362 from Creative biogene Species Reactivities Human

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