UGT1A4

Gene Symbol	UGT1A4
Entrez Gene	54657
Alt Symbol	HUG-BR2, UDPGT, UDPGT 1-4, UGT-1D, UGT1-04, UGT1.4, UGT1D
Species	Human
Gene Type	protein-coding
Description	UDP glucuronosyltransferase 1 family, polypeptide A4
Other Description	UDP glycosyltransferase 1 family, polypeptide A4|UDP-glucuronosyltransferase 1-4|UDP-glucuronosyltransferase 1-D|UDP-glucuronosyltransferase 1A4|bilirubin UDP-glucuronosyltransferase isozyme 2|bilirubin-specific UDPGT isozyme 2
Swissprots	B2R937 B8K288 P22310 Q5DT00
Accessions	AAA61249 AAG30422 AAL73503 AAL73504 AAL73505 AAY32626 AAY32627 AAY32628 AAY32629 ABE01866 ABE01867 ABE01868 ABE01869 ABE01870 ABE01871 ABE01872 ABE01873 ABE01874 ABE01875 ABE01876 ABE01877 EAW71061 P22310 AK313623 BAG36384 AY435139 AAR95640 BC121036 AAI21037 BC131623 AAI31624 BC139784 AAI39785 DQ364249 ABC96773 M57951 AAA63196 NM_007120 NP_009051
Function	UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX- alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity). {ECO:0000250}.
Subcellular Location	Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity	Isoform 1 and isoform 2 are expressed in liver, kidney, colon and small intestine. Isoform 2 but not isoform 1 is expressed in esophagus. Not expressed in skin. {ECO:0000269|PubMed:1339448, ECO:0000269|PubMed:18004212}.
Top Pathways	Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human UGT1A4 protein fragment - ab162806 from Abcam Category Protein Source Wheat germ Species Human

UGT1A4 Antibody Blocking Peptide - LS-E17033 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human UGT1A4 Protein - H00054657-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

UGT1A4 Blocking Peptide - 33R-9886 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

UGT1A4 - H00054657-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

UGT1A4 - H00054657-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human UGT1A4, MYC/DDK-tagged - UGT1A4-38H from Creative Biomart Category Protein Source HEK293 cells Species Human

UGT1A4 - TP319801 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

UGT1A4 Peptide, Human - M34GP17049H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human UGT1A4 protein - orb54137 from Biorbyt Category Protein Prices $298.00, $527.00, $612.00, $995.00, $1,649.00, $2,601.00 Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg Species Human

Recombinant Human UDP-glucuronosyltransferase 1-4(UGT1A4) - CSB-EP025577HU from Cusabio Category Protein Source E.coli Species Human

Recombinant Human UDP-glucuronosyltransferase 1-4(UGT1A4) - RPC20349 from Biomatik Category Protein Prices $156.00, $358.00, $561.00, $877.00, $1,395.00, $2,096.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Recombinant Human UDP-glucuronosyltransferase 1-4(UGT1A4) - RPC20367 from Biomatik Category Protein Prices $156.00, $358.00, $561.00, $877.00, $1,395.00, $2,096.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Recombinant Human UDP-glucuronosyltransferase 1-4(UGT1A4) - AP74587 from Signalway Antibody Category Protein Prices $155.00, $390.00, $665.00, $1,090.00, $1,835.00, $2,915.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Recombinant Human UDP-glucuronosyltransferase 1-4(UGT1A4) - AP74602 from Signalway Antibody Category Protein Prices $155.00, $390.00, $665.00, $1,090.00, $1,835.00, $2,915.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Recombinant Human UDP-glucuronosyltransferase 1-4(UGT1A4) ,partial,Yeast - CSB-YP025577HU from Cusabio Category Protein Source Yeast Species Human

UGT1A4 Recombinant Protein (Human) (OPCA04373) - OPCA04373 from Aviva Systems Biology Category Protein Species Human

UGT1A4 Recombinant Protein (Human) (OPCA04423) - OPCA04423 from Aviva Systems Biology Category Protein Species Human

Human UGT1A4 protein - orb383180 from Biorbyt Category Protein Species Human

Recombinant Human UGT1A4 Protein (29-534 aa), His-tagged - UGT1A4-2109H from Creative Biomart Category Protein Source E. coli Species Human

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