UGT1A4

Gene Symbol	UGT1A4
Entrez Gene	54657
Alt Symbol	HUG-BR2, UDPGT, UDPGT 1-4, UGT-1D, UGT1-04, UGT1.4, UGT1D
Species	Human
Gene Type	protein-coding
Description	UDP glucuronosyltransferase 1 family, polypeptide A4
Other Description	UDP glycosyltransferase 1 family, polypeptide A4|UDP-glucuronosyltransferase 1-4|UDP-glucuronosyltransferase 1-D|UDP-glucuronosyltransferase 1A4|bilirubin UDP-glucuronosyltransferase isozyme 2|bilirubin-specific UDPGT isozyme 2
Swissprots	B2R937 B8K288 P22310 Q5DT00
Accessions	AAA61249 AAG30422 AAL73503 AAL73504 AAL73505 AAY32626 AAY32627 AAY32628 AAY32629 ABE01866 ABE01867 ABE01868 ABE01869 ABE01870 ABE01871 ABE01872 ABE01873 ABE01874 ABE01875 ABE01876 ABE01877 EAW71061 P22310 AK313623 BAG36384 AY435139 AAR95640 BC121036 AAI21037 BC131623 AAI31624 BC139784 AAI39785 DQ364249 ABC96773 M57951 AAA63196 NM_007120 NP_009051
Function	UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX- alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity). {ECO:0000250}.
Subcellular Location	Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity	Isoform 1 and isoform 2 are expressed in liver, kidney, colon and small intestine. Isoform 2 but not isoform 1 is expressed in esophagus. Not expressed in skin. {ECO:0000269|PubMed:1339448, ECO:0000269|PubMed:18004212}.
Top Pathways	Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

UGT1A4 (L-14) - sc-27427 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-UGT1A4 antibody - ab192424 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-UGT1A4 antibody - ab105781 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-UGT1A4 Antibody (aa111-389) - LS-C311699 from LifeSpan Bioscience Prices $250.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-UGT1A4 Antibody - LS-C341648 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-UGT1A4 Antibody - LS-C334128 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-UGT1A4 Antibody (aa59-108) IHC-plus™ - LS-B8104 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

UGT1A4 Antibody - NBP1-69412 from Novus Biologicals Prices $329.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-UGT1A4 antibody produced in rabbit - AV46829 from Sigma-Aldrich Prices $347.50, $347.50 Sizes 50 µg, 100 µl Host Rabbit Clonality Polyclonal

Anti-UGT1A4 antibody produced in rabbit - SAB4300890 from Sigma-Aldrich Prices $230.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

UGT1A4 antibody - N-terminal region (ARP46829_P050) - ARP46829_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

UGT1A4 antibody - orb167418 from Biorbyt Prices $247.00, $374.00, $519.00 Sizes 50 μg, 100 μg, 200 μg Host Rabbit Clonality Polyclonal

UGT1A4 antibody - 70R-7257 from Fitzgerald Prices $345.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

UGT1A4 Polyclonal Antibody - A5549 from ABclonal Prices $130.00, $220.00, $380.00 Sizes 50 µl, 100 µl, 200 µl Host Rabbit Clonality Polyclonal

UGT1A4 Antibody - abx004248 from Abbexa Host Rabbit Clonality Polyclonal

UGT1A4 Antibody - 30-239 from ProSci Prices $315.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-UGT1A4 antibody - STJ27495 from St John's Laboratory Ltd Host Rabbit Clonality Polyclonal

UGT1A4 - A5549 from NeoScientific Prices $220.00, $380.00 Sizes 100 µl, 200 µl Host Rabbit Clonality Polyclonal

UGT1A4 Antibody - 32901 from Signalway Antibody Prices $279.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

UGT1A4 Antibody - GWB-MQ580D from Genway Biotech Prices $368.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

UGT1A4 , Polyclonal Antibody - MBS9125915 from MyBioSource Prices $230.00, $305.00, $460.00 Sizes 50 µl, 100 µl, 200 µl Host Rabbit Clonality Polyclonal

UGT1A4, Polyclonal Antibody - MBS2516797 from MyBioSource Prices $195.00, $270.00, $435.00 Sizes 60 µl, 120 µl, 200 µl Host Rabbit Clonality Polyclonal

UGT1A4 polyclonal antibody - BS7614 from Bioworld Technology Prices $208.00, $358.00 Sizes 50 µl, 100 µl Host Rabbit Clonality Polyclonal

UGT1A4-antibody-N-terminal-region-AI12720 - AI12720 from Abgent, a WuXi AppTec company Prices $293.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

UGT1A4 Antibody - DF7390 from Affinity Biosciences Prices $220.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Search more