Gene Symbol | SUSD4 |
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Entrez Gene | 55061 |
Alt Symbol | PRO222 |
Species | Human |
Gene Type | protein-coding |
Description | sushi domain containing 4 |
Other Description | YHGM196|sushi domain-containing protein 4 |
Swissprots | Q9NWG0 Q9BSR0 Q5VX71 Q6UX62 D3DTB9 |
Accessions | EAW93257 EAW93258 EAW93259 EAW93260 EAW93261 Q5VX71 AK000914 BAA91421 AK096265 BAG53242 AK295553 BAH12105 AK296923 BAH12455 AY358495 AAQ88859 BC004888 AAH04888 BF446433 DA125047 EF560748 ABQ59058 XM_005273169 XP_005273226 XM_005273172 XP_005273229 XM_006711408 XP_006711471 XM_011509685 XP_011507987 XM_011509686 XP_011507988 XM_011509687 XP_011507989 NM_001037175 NP_001032252 NM_017982 NP_060452 |
Function | Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways. {ECO:0000269|PubMed:23482636}. |
Subcellular Location | Isoform 1: Membrane {ECO:0000305}; Single- pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Isoform 3 is the predominant isoform in all tissues except cortex, cerebellum, kidney, and breast. Isoform 1 is found primarily in the esophagus and the brain. {ECO:0000269|PubMed:23482636}. |
SUSD4-Over-expression-Lysate - LY14531a from Abgent, a WuXi AppTec company
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SUSD4 293T Cell Transient Overexpression Lysate(Denatured) - H00055061-T01 from Acris Antibodies
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SUSD4 overexpression lysate - LY421931 from Acris Antibodies
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SUSD4 293 Cell Lysate - 409600 from ABBIOTEC
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SUSD4 293 Cell Lysate - 406487 from ABBIOTEC
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SUSD4 Overexpression Lysate (Native) - NBL1-16624 from Novus Biologicals
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SUSD4 Overexpression Lysate (Native) - NBP2-06892 from Novus Biologicals
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SUSD4 Over-expression Lysate Product - GWB-6B7B4E from Genway Biotech
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SUSD4 Over-expression Lysate Product - GWB-5B5ABA from Genway Biotech
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Human SUSD4 / Sushi domain-containing HEK293 Cell Lysate (WB positive control) - 13488-H05HL-300 from Sino Biological
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SUSD4 Overexpression Lysate (Native) - NBP2-09885 from Novus Biologicals
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SUSD4 Overexpression Lysate (Denatured) - H00055061-T01 from Novus Biologicals
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Human SUSD4 Human Cells Transfected Lysate (positive control) (denatured) - orb174855 from Biorbyt
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Panoply™ Human SUSD4 Knockdown Stable Cell Line - CSC-DC015426 from Creative biogene
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