Gene Symbol | SUSD4 |
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Entrez Gene | 55061 |
Alt Symbol | PRO222 |
Species | Human |
Gene Type | protein-coding |
Description | sushi domain containing 4 |
Other Description | YHGM196|sushi domain-containing protein 4 |
Swissprots | Q9NWG0 Q9BSR0 Q5VX71 Q6UX62 D3DTB9 |
Accessions | EAW93257 EAW93258 EAW93259 EAW93260 EAW93261 Q5VX71 AK000914 BAA91421 AK096265 BAG53242 AK295553 BAH12105 AK296923 BAH12455 AY358495 AAQ88859 BC004888 AAH04888 BF446433 DA125047 EF560748 ABQ59058 XM_005273169 XP_005273226 XM_005273172 XP_005273229 XM_006711408 XP_006711471 XM_011509685 XP_011507987 XM_011509686 XP_011507988 XM_011509687 XP_011507989 NM_001037175 NP_001032252 NM_017982 NP_060452 |
Function | Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways. {ECO:0000269|PubMed:23482636}. |
Subcellular Location | Isoform 1: Membrane {ECO:0000305}; Single- pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Isoform 3 is the predominant isoform in all tissues except cortex, cerebellum, kidney, and breast. Isoform 1 is found primarily in the esophagus and the brain. {ECO:0000269|PubMed:23482636}. |
Human SUSD4 full length protein - ab162947 from Abcam
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SUSD4 Antibody Blocking Peptide - LS-E17173 from LifeSpan Bioscience
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SUSD4 Antibody Blocking Peptide - LS-E17174 from LifeSpan Bioscience
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Recombinant Human SUSD4 Protein - H00055061-P01 from Novus Biologicals
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SUSD4 Blocking Peptide - 33R-3734 from Fitzgerald
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SUSD4 Blocking Peptide - 33R-6626 from Fitzgerald
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SUSD4 - H00055061-P01-10 from Acris Antibodies
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SUSD4 - H00055061-P01-25 from Acris Antibodies
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Recombinant Human SUSD4, Fc tagged - SUSD4-138H from Creative Biomart
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Human SUSD4 / Sushi domain-containing Protein 4 Protein (Fc Tag) - 13488-H05H-20 from Sino Biological
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Recombinant Human Sushi domain-containing protein 4(SUSD4) - CSB-YP733164HU CSB-EP733164HU CSB-BP733164HU CSB-MP733164HU from Cusabio
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SUSD4 (transcript variant 2) - TP302622 from Acris Antibodies
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Recombinant Human SUSD4 / Sushi domain-containing protein 4 Protein (Fc tag) - PKSH030623 from Elabscience
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Human SUSD4 protein - orb139715 from Biorbyt
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SUSD4 Protein - NBP2-31711PEP from Novus Biologicals
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SUSD4 fusion protein - Ag25346 from Proteintech Group
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SUSD4-Antibody-N-term-Blocking-Peptide - BP5170a from Abgent, a WuXi AppTec company
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SUSD4 Peptide, Human - M34GP15426H from Creative Peptides
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SUSD4 / Sushi domain-containing 4, Recombinant Protein - MBS2545305 from MyBioSource
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Sushi domain-containing protein 4 (SUSD4), Recombinant Protein - MBS1443128 from MyBioSource
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