Gene Symbol | SUSD4 |
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Entrez Gene | 55061 |
Alt Symbol | PRO222 |
Species | Human |
Gene Type | protein-coding |
Description | sushi domain containing 4 |
Other Description | YHGM196|sushi domain-containing protein 4 |
Swissprots | Q9NWG0 Q9BSR0 Q5VX71 Q6UX62 D3DTB9 |
Accessions | EAW93257 EAW93258 EAW93259 EAW93260 EAW93261 Q5VX71 AK000914 BAA91421 AK096265 BAG53242 AK295553 BAH12105 AK296923 BAH12455 AY358495 AAQ88859 BC004888 AAH04888 BF446433 DA125047 EF560748 ABQ59058 XM_005273169 XP_005273226 XM_005273172 XP_005273229 XM_006711408 XP_006711471 XM_011509685 XP_011507987 XM_011509686 XP_011507988 XM_011509687 XP_011507989 NM_001037175 NP_001032252 NM_017982 NP_060452 |
Function | Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways. {ECO:0000269|PubMed:23482636}. |
Subcellular Location | Isoform 1: Membrane {ECO:0000305}; Single- pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Isoform 3 is the predominant isoform in all tissues except cortex, cerebellum, kidney, and breast. Isoform 1 is found primarily in the esophagus and the brain. {ECO:0000269|PubMed:23482636}. |
SUSD4 (S-16) - sc-248743 from Santa Cruz Biotechnology
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Anti-SUSD4 antibody - ab82809 from Abcam
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Anti-SUSD4 antibody - ab169678 from Abcam
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Anti-SUSD4 Antibody (aa251-300) - LS-C107960 from LifeSpan Bioscience
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Anti-SUSD4 Antibody (N-Terminus) - LS-C81041 from LifeSpan Bioscience
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SUSD4 Antibody - NBP2-31711 from Novus Biologicals
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SUSD4 Antibody - NBP1-59975 from Novus Biologicals
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SUSD4 Antibody - NBP1-59974 from Novus Biologicals
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Anti-SUSD4 antibody produced in rabbit - HPA058296 from Sigma-Aldrich
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Anti-SUSD4 antibody produced in rabbit - SAB2105162 from Sigma-Aldrich
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Anti-SUSD4 antibody produced in rabbit - SAB2102341 from Sigma-Aldrich
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Anti-SUSD4 antibody produced in mouse - SAB1407608 from Sigma-Aldrich
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Anti-SUSD4 (126-140) antibody produced in rabbit - SAB1102151 from Sigma-Aldrich
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SUSD4 antibody - N-terminal region (ARP47383_P050) - ARP47383_P050 from Aviva Systems Biology
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SUSD4 antibody - middle region (ARP47384_P050) - ARP47384_P050 from Aviva Systems Biology
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SUSD4 antibody - 70R-6884 from Fitzgerald
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SUSD4 antibody - 70R-6885 from Fitzgerald
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SUSD4 antibody - H00055061-B01P from Acris Antibodies
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SUSD4 Antibody - 26-218 from ProSci
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SUSD4 Antibody - GWB-MQ748A from Genway Biotech
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SUSD4 Antibody - GWB-MQ749B from Genway Biotech
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Anti-SUSD4 (full length) polyclonal antibody - DPABH-08260 from Creative Diagnostics
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SUSD4, Polyclonal Antibody - MBS6009066 from MyBioSource
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SUSD4 Antibody - H00055061-B01P from Novus Biologicals
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SUSD4, Polyclonal Antibody - MBS5300645 from MyBioSource
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