Gene Symbol | PTH2R |
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Entrez Gene | 5746 |
Alt Symbol | PTHR2 |
Species | Human |
Gene Type | protein-coding |
Description | parathyroid hormone 2 receptor |
Other Description | PTH2 receptor|parathyroid hormone receptor 2 |
Swissprots | P49190 Q8N429 |
Accessions | AAA96796 AAY14871 AAY15091 EAW70451 P49190 AK294181 BAG57499 AK309827 AY497546 AAR90849 BC036811 AAH36811 BM808818 CR747526 DB536374 HQ257935 ADR82689 U25128 AAC50157 XM_011511517 XP_011509819 XR_922972 NM_005048 NP_005039 NR_073601 |
Function | This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed abundantly in brain and pancreas. Also expressed in the testis. {ECO:0000269|PubMed:7797535}. |
Top Pathways | Neuroactive ligand-receptor interaction |
PTH2 Receptor (H-60) - sc-30005 from Santa Cruz Biotechnology
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PTH2 Receptor (E-20) - sc-16384 from Santa Cruz Biotechnology
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PTH2 Receptor (V-20) - sc-16385 from Santa Cruz Biotechnology
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Anti-Parathyroid Hormone Receptor 2 antibody - ab115688 from Abcam
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Anti-Parathyroid Hormone Receptor 2 antibody - ab35115 from Abcam
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Anti-Parathyroid Hormone Receptor 2 antibody - ab133924 from Abcam
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Anti-Parathyroid Hormone Receptor 2 antibody - Extracellular domain - ab188760 from Abcam
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Anti-PTHR2 / PTH2R Antibody (aa99-116) - LS-C41551 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody - LS-C93048 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody - LS-C292490 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody - LS-C292492 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody - LS-C292494 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody (Biotin) - LS-C298925 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody (Biotin) - LS-C298926 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody (Biotin) - LS-C298927 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody (FITC) - LS-C302873 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody (FITC) - LS-C302874 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody (FITC) - LS-C302876 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody (HRP) - LS-C317886 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody (C-Terminus) - LS-C151851 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody (FITC) - LS-C317887 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody (Biotin) - LS-C317888 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody - LS-C317889 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody (C-Terminus) IHC-plus™ - LS-A250 from LifeSpan Bioscience
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Anti-PTHR2 / PTH2R Antibody (aa27-145) - LS-C314518 from LifeSpan Bioscience
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