Gene Symbol | PTH2R |
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Entrez Gene | 5746 |
Alt Symbol | PTHR2 |
Species | Human |
Gene Type | protein-coding |
Description | parathyroid hormone 2 receptor |
Other Description | PTH2 receptor|parathyroid hormone receptor 2 |
Swissprots | P49190 Q8N429 |
Accessions | AAA96796 AAY14871 AAY15091 EAW70451 P49190 AK294181 BAG57499 AK309827 AY497546 AAR90849 BC036811 AAH36811 BM808818 CR747526 DB536374 HQ257935 ADR82689 U25128 AAC50157 XM_011511517 XP_011509819 XR_922972 NM_005048 NP_005039 NR_073601 |
Function | This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed abundantly in brain and pancreas. Also expressed in the testis. {ECO:0000269|PubMed:7797535}. |
Top Pathways | Neuroactive ligand-receptor interaction |
PTHR2 / PTH2R Antibody Blocking Peptide - LS-E23663 from LifeSpan Bioscience
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PTHR2 / PTH2R Blocking Peptide - LS-E28561 from LifeSpan Bioscience
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PTHR2 / PTH2R Antibody Blocking Peptide - LS-E28563 from LifeSpan Bioscience
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PTHR2 / PTH2R Antibody Blocking Peptide - LS-E28562 from LifeSpan Bioscience
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Recombinant Human PTH2R Protein - H00005746-G01-10ug from Novus Biologicals
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PTH2R-Antibody-Center-Blocking-Peptide - BP9263c from Abgent, a WuXi AppTec company
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Human PTH2R protein - orb244472 from Biorbyt
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PTH2R fusion protein - ag5785 from Proteintech Group
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PTH2R fusion protein - Ag5364 from Proteintech Group
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Recombinant Parathyroid Hormone Receptor 2 (PTHR2) - RPA474Hu01 from Uscn Life Science Inc.
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Recombinant Parathyroid Hormone Receptor 2 (PTHR2) - RPA474Ra01 from Uscn Life Science Inc.
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Recombinant human Parathyroid hormone 2 receptor - CSB-YP018990HU CSB-BP018990HU CSB-MP018990HU from Cusabio
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Recombinant human Parathyroid hormone 2 receptor - CSB-EP018990HU from Cusabio
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Parathyroid Hormone Receptor 2 Protein (Recombinant) - abx166560 from Abbexa
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PTHR2 / PTH2R Blocking Peptide - LS-E39743 from LifeSpan Bioscience
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Parathyroid hormone 2 receptor, Recombinant Protein - MBS949987 from MyBioSource
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PTH2R Recombinant Protein Antigen - NBP2-34199PEP from Novus Biologicals
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PTH2R Peptide, Human - M34GP12676H from Creative Peptides
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PTH2R Recombinant Protein (OPCA01806) - OPCA01806 from Aviva Systems Biology
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Recombinant Parathyroid Hormone Receptor 2 (PTHR2) - RPU51740 from Biomatik
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PTH2R Recombinant Protein (OPCD06495) - OPCD06495 from Aviva Systems Biology
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Recombinant human Parathyroid hormone 2 receptor - AP70680 from Signalway Antibody
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Parathyroid hormone 2 receptor, Recombinant Protein - MBS9420580 from MyBioSource
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Parathyroid hormone 2 receptor (PTH2R), Recombinant Protein - MBS7028235 from MyBioSource
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