ENPP6

Gene Symbol	ENPP6
Entrez Gene	133121
Alt Symbol	NPP6
Species	Human
Gene Type	protein-coding
Description	ectonucleotide pyrophosphatase/phosphodiesterase 6
Other Description	B830047L21Rik|E-NPP 6|GPC-Cpde|NPP-6|choline-specific glycerophosphodiester phosphodiesterase|ectonucleotide pyrophosphatase/phosphodiesterase family member 6|glycerophosphocholine cholinephosphodiesterase
Swissprots	Q96M57 Q4W5Q1 Q6UWR7
Accessions	AAY40908 EAX04683 Q6UWR7 AK021943 AK057370 BAB71455 AK308585 AY358676 AAQ89039 BC035035 AAH35035 NM_153343 NP_699174
Function	Choline-specific glycerophosphodiester phosphodiesterase. The preferred substrate may be lysosphingomyelin (By similarity). Hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine in vitro, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'- monophosphate. Does not hydrolyze diacyl phospholipids such as phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, phosphatidylglycerol and phosphatidic acid. {ECO:0000250, ECO:0000269|PubMed:15788404}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:15788404}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:15788404}. Note=A small amount of the protein may be found in the extracellular milieu.
Tissue Specificity	Predominantly expressed in kidney and brain. In the kidney, expressed specifically in the proximal tubules and thin descending limbs of Henle (at protein level). {ECO:0000269|PubMed:15788404}.
Top Pathways	Ether lipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ectonucleotide pyrophosphatase/phosphodiesterase 6, ELISA Kit - MBS9327272 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/ml. Range 0.25 ng/ml - 8 ng/ml.

Human ENPP6 ELISA Kit - E082345 from Biobool Category ELISA Kit

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9367825 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9364442 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9347610 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9363032 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9357011 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9346514 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9365536 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9367384 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9357604 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9347666 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9347539 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9343527 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9357020 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9345890 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9361442 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9380233 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9349279 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9357580 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9353111 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 6 (ENPP6), ELISA Kit - MBS9345400 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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