CRACR2A

Gene Symbol	CRACR2A
Entrez Gene	84766
Alt Symbol	EFCAB4B
Species	Human
Gene Type	protein-coding
Description	calcium release activated channel regulator 2A
Other Description	CRAC channel regulator 2A|CRAC regulator 2A|Ca2+ release-activated Ca2+ (CRAC) channel regulator 2A|EF-hand calcium binding domain 4B|EF-hand calcium-binding domain-containing protein 4B|calcium release-activated calcium channel regulator 2A|calcium release-activated channel regulator 2A
Swissprots	Q9BSW2 B4E1X0 B9EK63
Accessions	EAW88858 EAW88859 EAW88860 Q9BSW2 AK057608 AK091124 AK304017 BAG64932 BC004524 AAH04524 BC150643 AAI50644 BU632650 BU634271 CR627161 DB214079 JF432156 ADZ15373 XM_006719021 XP_006719084 XM_011521034 XP_011519336 XM_011521035 XP_011519337 XM_011521036 XP_011519338 XM_011521037 XP_011519339 XM_011521038 XP_011519340 NM_001144959 NM_001144958 NP_001138430 NM_032680 NP_116069
Function	Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex. {ECO:0000269|PubMed:20418871}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:20418871}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EFCAB4B - MBS1271966 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC004524

Human EFCAB4B cDNA clone(NM_001144958.1) - CDFH005686 from Creative Biomart Species Human Accession NM_001144958.1

Human EFCAB4B ORF Clone(NM_032680.3) - CDCL161933 from Creative Biomart Species Human Accession NM_032680.3

Human EFCAB4B ORF Clone(NM_001144958.1) - CDCR352299 from Creative Biomart Species Human Accession NM_001144958.1

Human EFCAB4B ORF Clone(NM_001144958.1) - CDCR352300 from Creative Biomart Species Human Accession NM_001144958.1

Human EFCAB4B Gene ORF cDNA clone in cloning vector - HG14761-G from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid, C-His tag - HG14761-CH from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14761-CF from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14761-ANG from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14761-NM from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14761-CM from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid - HG14761-UT from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid, C-HA tag - HG14761-CY from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14761-ACR from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14761-ANR from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14761-ACG from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid, N-HA tag - HG14761-NY from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid, N-His tag - HG14761-NH from Sino Biological Species Human

Human EFCAB4B Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14761-NF from Sino Biological Species Human

Human EFCAB4B ORF clone (NM_001144958.1) - CDCR058848 from Creative biogene Species Human

Human EFCAB4B ORF Clone (BC004524) - CDCS408430 from Creative biogene Species Human Accession Q9BSW2

Human EFCAB4B ORF clone (BC004524) - CDCB158565 from Creative biogene Species Human

Human EFCAB4B cDNA Clone(NM_001144958.1) - CDFH005686 from Creative biogene Species Human

Human EFCAB4B Gene cDNA Clone - orb142966 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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