DKK3

Gene Symbol	DKK3
Entrez Gene	27122
Alt Symbol	REIC, RIG
Species	Human
Gene Type	protein-coding
Description	dickkopf WNT signaling pathway inhibitor 3
Other Description	RIG-like 5-6|RIG-like 7-1|dickkopf 3 homolog|dickkopf homolog 3|dickkopf-3|dickkopf-related protein 3|dkk-3|hDkk-3|regulated in glioma
Swissprots	Q9ULB7 A8K1I2 D3DQW1 Q9UBP4
Accessions	BAA87044 BAB84361 EAW68533 EAW68534 EAW68535 EAW68536 EAW68537 EAW68538 EAW68539 Q9UBP4 AB033421 BAA85488 AB034203 BAA90548 AB057591 BAB84360 AF052161 AF177396 AAF02676 AF400439 AAK92488 AK090952 BAC03555 AK092979 BAG52632 AK098756 AK225156 AK289897 BAF82586 AK295441 BAG58381 AK295539 BAG58448 AL535720 AY358378 AAQ88744 AY587550 AAS86757 BC007660 AAH07660 BQ690088 BQ690888 CB156451 DQ892906 ABM83832 DQ896157 ABM87156 H18461 U32331 AAC35996 XM_006718178 XP_006718241 NM_001018057 NP_001018067 NM_013253 NP_037385 NM_015881 NP_056965
Function	Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). {ECO:0000250}.
Subcellular Location	Secreted.
Tissue Specificity	Highest expression in heart, brain, and spinal cord. {ECO:0000269|PubMed:10570958, ECO:0000269|Ref.4}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DKK3 (Dickkopf-3) Human ELISA Kit - ab100502 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 3 pg/ml Range 2.74 pg/ml - 2000 pg/ml

Human DKK3 ELISA Kit (Sandwich ELISA) - LS-F2977 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 2.743-666.7 pg/ml

Human DKK3 ELISA Kit (Sandwich ELISA) - LS-F65 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 2.743 pg/ml Range 2.743-666.7 pg/ml

Rat DKK3 ELISA Kit (Sandwich ELISA) - LS-F8911 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 14.3 pg/ml Range 2.743-666.7 pg/ml

Human DKK3 ELISA Kit (Sandwich ELISA) - LS-F11303 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 62.5 Range 2.743-666.7 pg/ml

Human Dkk-3 ELISA Kit - RAB0145 from Sigma-Aldrich Category ELISA Kit Prices $438.50 Sizes 1 kt

Human Dkk-3 DuoSet ELISA - DY1118 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 31.20 - 2,000 pg/mL

Human DKK3 ELISA kit - 55R-2047 from Fitzgerald Category ELISA Kit Prices $505.00 Sizes 96 tests

DKK3 ELISA Kit - orb182349 from Biorbyt Category ELISA Kit Prices $570.00 Sizes 96 well Sensitivity < 10 pg/ml Range 156 pg/ml-10000 pg/ml

Dickkopf 3, DKK3, Human, ELISA Kit - CSB-E13607h from ARP American Research Products Category ELISA Kit Prices $338.00, $468.00, $469.00, $471.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Dickkopf-related protein 3, DKK3, Human, ELISA Kit - E6373h from ARP American Research Products Category ELISA Kit Prices $576.00 Sizes 96 t Range 62.5-4000 pg/mL

DKK3 (Human) ELISA Kit - KA1706 from Acris Antibodies Category ELISA Kit Prices $650.00 Sizes 1 kit

Human Dkk-3 ELISA - ELH-DKK3 from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,561.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 3 pg/ml Range 3 pg/ml - 2000 pg/ml

Dickkopf Related Protein 3 (DKK3), ELISA Kit - MBS2019294 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 14.3pg/mL. Range 31.25-2000pg/mL

DKK3 Human ELISA Kit - DEIA1442 from Creative Diagnostics Category ELISA Kit Sensitivity The minimum detectable dose of DKK3 is typically less than 3 pg/mL. Range 2.74 pg/mL - 2000 pg/mL

dickkopf homolog 3 (Xenopus laevis) , ELISA Kit - MBS702230 from MyBioSource Category ELISA Kit Prices $250.00, $620.00, $2,180.00, $4,120.00 Sizes 24 -strip-wells (Limit 1), 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DKK-3, ELISA Kit - MBS177233 from MyBioSource Category ELISA Kit Prices $425.00 Sizes 1x96 wells Sensitivity < 10pg/ml Range 156pg/ml-10,000pg/ml

DKK3, ELISA Kit - MBS2515976 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

DKK3, ELISA Kit - MBS2516005 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 37.5pg/mL Range 62.5-4000pg/mL

DKK3, ELISA Kit - MBS2515630 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625-1000pg/mL

Mouse DKK3 ELISA Pair Set - SEK50247-5 from Sino Biological Category ELISA Kit Prices $350.00, $350.00 Sizes 5 plates, 15 plates Sensitivity 15.625 pg/ml

Human DKK3 / Dkk-3 / REIC ELISA Pair Set - SEK10203-5 from Sino Biological Category ELISA Kit Prices $350.00, $350.00 Sizes 5 plates, 15 plates Sensitivity 62.5 pg/ml

ELISA Kit for Dickkopf Related Protein 3 (DKK3) - SED410Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.057ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Dickkopf Related Protein 3 (DKK3) - SED410Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 14.3pg/mL. Range 31.25-2000pg/mL The standard curve concentrations used for the ELISA’s were 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL

Human DKK-3 PicoKine™ ELISA Kit EK1323 - EK1323 from Boster Bio Category ELISA Kit Prices $369.00 Sizes 1 kit Sensitivity <10pg/ml Range 156pg/ml-10,000pg/ml *This assay range is determined using common samples. For samples with low target protein concentrations, users can adjust the standard curve to extend the lower limit of assay range.

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