DEFA5

Gene Symbol	DEFA5
Entrez Gene	1670
Alt Symbol	DEF5, HD-5
Species	Human
Gene Type	protein-coding
Description	defensin, alpha 5, Paneth cell-specific
Other Description	HD5(20-94)|defensin 5|defensin, alpha 5, preproprotein|defensin-5
Swissprots	Q3KNV2 A0JDY6 Q01523
Accessions	AAA35754 AAT68886 EAW80489 Q01523 BC069690 AAH69690 BC107079 AAI07080 BM854660 BP419449 HQ448430 ADQ32910 NM_021010 NP_066290
Function	Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing. {ECO:0000269|PubMed:12021776, ECO:0000269|PubMed:15616305, ECO:0000269|PubMed:17088326}.
Subcellular Location	Secreted {ECO:0000269|PubMed:12021776}. Cytoplasmic vesicle, secretory vesicle {ECO:0000269|PubMed:12021776}. Note=Peptides HD5(20-94), HD5(23- 94) and HD5(29-94) are found within tissues, HD5(20-94) being the predominant intracellular form. Peptides HD5(56-94) and HD5(63-94) are found in the extracellular milieu, HD5(63-94) being the most abundant form.
Tissue Specificity	Paneth cells of the small intestine (at protein level). {ECO:0000269|PubMed:12021776}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse DEFA5 / Defensin 5 ELISA Kit (Sandwich ELISA) - LS-F5429 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 13.7 pg/ml Range 31.25-2000 pg/ml

Human DEFA5 / Defensin 5 ELISA Kit (Sandwich ELISA) - LS-F5725 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 15.63 pg/ml Range 31.25-2000 pg/ml

Human DEFA5 / Defensin 5 ELISA Kit (Sandwich ELISA) - LS-F11288 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 15.6 Range 31.25-2000 pg/ml

Human DEFa5 ELISA Kit - abx151275 from Abbexa Category ELISA Kit Sensitivity 6.4 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Defensin Alpha 5, Paneth Cell Specific, DEFa5, Human, ELISA Kit - E-EL-H1798 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Defensin 5, Human, ELISA Kit - E01D0005 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Defensin Alpha 5, Paneth Cell Specific (DEFa5), Human, ELISA Kit - SEB912Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 1.31pg/mL Range 3.12-200pg/mL

Defensin-5 (DEFA5), Human, ELISA Kit - CSB-EL006657HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Defensin-5, DEFA5, Human, ELISA Kit - E1718h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 15.6-1000 pg/mL

Defensin Alpha 5, Paneth Cell Specific, DEFa5, Mouse, ELISA Kit - E-EL-M0403 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Defensin-5, D-5, Rat, ELISA Kit - E-EL-R0322 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Defensin Alpha 5, Paneth Cell Specific, DEFa5, Rabbit, ELISA Kit - E-EL-RB1976 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Defensin Alpha 5, Paneth Cell Specific, DEFa5, Chicken, ELISA Kit - E-EL-Ch1974 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Defensin Alpha 5, Paneth Cell Specific, DEFa5, Porcine, ELISA Kit - E-EL-P0326 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Defensin Alpha 5, Paneth Cell Specific, DEFa5, Sheep, ELISA Kit - E-EL-S0247 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Defensin Alpha 5, Paneth Cell Specific, DEFa5, Guinea Pig, ELISA Kit - E-EL-GP0307 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Defensin Alpha 5, Paneth Cell Specific, DEFa5, Monkey, ELISA Kit - E-EL-MK1117 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Defensin Alpha 5 Paneth Cell Specific, ELISA Kit - MBS723991 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Defensin Alpha 5 Paneth Cell Specific, ELISA Kit - MBS734857 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Defensin Alpha 5 Paneth Cell Specific, ELISA Kit - MBS728264 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Defensin Alpha 5 Paneth Cell Specific, ELISA Kit - MBS730873 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Defensin Alpha 5, Paneth Cell Specific, ELISA Kit - MBS040984 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Defensin Alpha 5, Paneth Cell Specific, ELISA Kit - MBS065344 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Defensin Alpha 5, Paneth Cell Specific, ELISA Kit - MBS726865 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Defensin Alpha 5, Paneth Cell Specific, ELISA Kit - MBS739667 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

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