DEFA5

Gene Symbol	DEFA5
Entrez Gene	1670
Alt Symbol	DEF5, HD-5
Species	Human
Gene Type	protein-coding
Description	defensin, alpha 5, Paneth cell-specific
Other Description	HD5(20-94)|defensin 5|defensin, alpha 5, preproprotein|defensin-5
Swissprots	Q3KNV2 A0JDY6 Q01523
Accessions	AAA35754 AAT68886 EAW80489 Q01523 BC069690 AAH69690 BC107079 AAI07080 BM854660 BP419449 HQ448430 ADQ32910 NM_021010 NP_066290
Function	Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing. {ECO:0000269|PubMed:12021776, ECO:0000269|PubMed:15616305, ECO:0000269|PubMed:17088326}.
Subcellular Location	Secreted {ECO:0000269|PubMed:12021776}. Cytoplasmic vesicle, secretory vesicle {ECO:0000269|PubMed:12021776}. Note=Peptides HD5(20-94), HD5(23- 94) and HD5(29-94) are found within tissues, HD5(20-94) being the predominant intracellular form. Peptides HD5(56-94) and HD5(63-94) are found in the extracellular milieu, HD5(63-94) being the most abundant form.
Tissue Specificity	Paneth cells of the small intestine (at protein level). {ECO:0000269|PubMed:12021776}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human alpha 5 Defensin full length protein - ab158273 from Abcam Category Protein Prices $402.00 Sizes 2 µg Source Wheat germ Species Human

Recombinant Human Defensin alpha 5 Protein - H00001670-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Defensin alpha 5 Protein - GTX116079-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

Human DEFa5 Protein - abx066285 from Abbexa Category Protein Source E.coli Species Human

Defensin alpha 5 - H00001670-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Defensin alpha 5 - H00001670-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Defensin Alpha 5, Paneth Cell Specific (DEFa5), Human - 20-8142 from ARP American Research Products Category Protein Prices $505.00 Sizes 50 µg Source E.coli Species Human

DEFA5 fusion protein - Ag12793 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

DEFA5 fusion protein - ag12938 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human DEFA5, GST-tagged - DEFA5-11927H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Defensin Alpha 5, Paneth Cell Specific (DEFa5) - RPB912Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Defensin Alpha 5, Paneth Cell Specific (DEFa5) - RPB912Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Defensin alpha 5 - TP310219 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Defensin alpha 5 Recombinant Protein Antigen - NBP1-84282PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DEFA5 Peptide, Human - M34GP04184H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human Defensin-5 - AF2076 from Creative Peptides Category Peptide Source Homo sapiens Species Human

DEFA5 Recombinant Protein (OPCD02706) - OPCD02706 from Aviva Systems Biology Category Protein Source E.coli Species Human

Defensin Alpha 5, Paneth Cell Specific (DEFa5), Recombinant Protein - MBS2010028 from MyBioSource Category Protein Prices $185.00, $390.00, $605.00 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

Defensin-5 (DEFA5), Recombinant Protein - MBS1332281 from MyBioSource Category Protein Prices $805.00, $805.00, $1,030.00, $1,030.00, $1,135.00, $1,135.00, $1,590.00, $1,590.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Chimpanzee

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