Sirt3

Gene Symbol	Sirt3
Entrez Gene	64384
Alt Symbol	2310003L23Rik, AI848213, Sir2l3
Species	Mouse
Gene Type	protein-coding
Description	sirtuin 3
Other Description	NAD-dependent deacetylase sirtuin-3|NAD-dependent protein deacetylase sirtuin-3|SIR2-like protein 3|SIRT3L mitochondrial|mSIR2L3|mitochondrial protein lysine deacetylase|regulatory protein SIR2 homolog 3|silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3
Swissprots	C6ZII7 Q9EPA8 Q8R104 B9W0A9
Accessions	AAG33227 EDL17961 EDL17962 EDL17963 Q8R104 AF299338 AAG39257 AF299339 AAG39258 AK075861 BAC36012 AK086910 AK165407 BC025878 AAH25878 BF681854 CB953804 CT010402 CAJ18608 EU886466 ACJ70655 FJ621493 ACM68947 XM_006536222 XP_006536285 XM_006536223 XP_006536286 NM_001127351 NP_001120823 NM_001177804 NP_001171275 NM_022433 NP_071878
Function	NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, PDHA1, SOD2, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels. {ECO:0000269|PubMed:16790548, ECO:0000269|PubMed:17923681, ECO:0000269|PubMed:18794531, ECO:0000269|PubMed:21172655, ECO:0000269|PubMed:21858060, ECO:0000269|PubMed:23835326, ECO:0000269|PubMed:24252090}.
Subcellular Location	Isoform L: Mitochondrion matrix.
Tissue Specificity	Strongly expressed in liver and kidney. Weakly expressed in lung. {ECO:0000269|PubMed:11056054}.
Top Pathways	Central carbon metabolism in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

NAD-dependent deacetylase sirtuin-3, Sirt3, Mouse, ELISA Kit - E2135m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

Sirtuin 3 (SIRT3), Mouse, ELISA Kit - SEE913Mu from ARP American Research Products Category ELISA Kit Prices $740.00 Sizes 96 t Sensitivity 0.055ng/mL Range 0.156-10ng/mL

sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) , ELISA Kit - MBS9324962 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sirtuin 3 (SIRT3), ELISA Kit - MBS2023250 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.054ng/mL. Range 0.156-10ng/mL

ELISA Kit for Sirtuin 3 (SIRT3) - SEE913Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Mouse Sirtuin 3 (SIRT3) ELISA Kit - EKU07353 from Biomatik Category ELISA Kit Prices $756.00, $3,326.00, $6,048.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.054 ng/mL Range 0.156-10 ng/mL

Mouse NAD-dependent deacetylase sirtuin-3 ELISA Kit - abx255079 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Mouse Sirtuin 3 ELISA Kit - abx154678 from Abbexa Category ELISA Kit Sensitivity 0.055 ng/ml Range 0.156 ng/ml - 10 ng/ml

Mouse SIRT3 ELISA Kit - abx571833 from Abbexa Category ELISA Kit Sensitivity 0.055 ng/ml Range 0.156 ng/ml - 10 ng/ml

Mouse NAD-dependent deacetylase sirtuin-3 ELISA Kit - EKE53416 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Range 0.312-20 ng/mL

Sirt3 - EKM1462 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

Mouse Sirt3 ELISA Kit - E061065 from Biobool Category ELISA Kit

SIRT3 ELISA Kit (Mouse) (OKEH03459) - OKEH03459 from Aviva Systems Biology Category ELISA Kit Prices $425.00 Sizes 96 wells Sensitivity 0.156 ng/mL Range 0.312 - 20 ng/mL

Mouse NAD-dependent deacetylase sirtuin-3 ELISA Kit - EK4316 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Sensitivity less than 0.78 ng/mL Range 1.56-100 ng/mL

Mouse NAD-dependent deacetylase sirtuin-3, mitochondrial (SIRT3) ELISA Kit - AE19476MO from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.054 ng/mL Range 0.156-10 ng/mL

NAD-dependent deacetylase sirtuin-3, ELISA Kit - MBS2885911 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

NAD-dependent deacetylase sirtuin-3, ELISA Kit - MBS760932 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/ml Range 0.312-20ng/ml

NAD-dependent deacetylase sirtuin-3, ELISA Kit - MBS9428142 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Range 0.312-20 ng/mL

Sirtuin 3 (SIRT3), ELISA Kit - MBS456311 from MyBioSource Category ELISA Kit Prices $425.00, $560.00, $2,480.00, $4,820.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.055ng/mL Range 0.156-10ng/mL

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