Sirt3

Gene Symbol Sirt3
Entrez Gene 64384
Alt Symbol 2310003L23Rik, AI848213, Sir2l3
Species Mouse
Gene Type protein-coding
Description sirtuin 3
Other Description NAD-dependent deacetylase sirtuin-3|NAD-dependent protein deacetylase sirtuin-3|SIR2-like protein 3|SIRT3L mitochondrial|mSIR2L3|mitochondrial protein lysine deacetylase|regulatory protein SIR2 homolog 3|silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3
Swissprots C6ZII7 Q9EPA8 Q8R104 B9W0A9
Accessions AAG33227 EDL17961 EDL17962 EDL17963 Q8R104 AF299338 AAG39257 AF299339 AAG39258 AK075861 BAC36012 AK086910 AK165407 BC025878 AAH25878 BF681854 CB953804 CT010402 CAJ18608 EU886466 ACJ70655 FJ621493 ACM68947 XM_006536222 XP_006536285 XM_006536223 XP_006536286 NM_001127351 NP_001120823 NM_001177804 NP_001171275 NM_022433 NP_071878
Function NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, PDHA1, SOD2, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels. {ECO:0000269|PubMed:16790548, ECO:0000269|PubMed:17923681, ECO:0000269|PubMed:18794531, ECO:0000269|PubMed:21172655, ECO:0000269|PubMed:21858060, ECO:0000269|PubMed:23835326, ECO:0000269|PubMed:24252090}.
Subcellular Location Isoform L: Mitochondrion matrix.
Tissue Specificity Strongly expressed in liver and kidney. Weakly expressed in lung. {ECO:0000269|PubMed:11056054}.
Top Pathways Central carbon metabolism in cancer

Anti-SIRT3 antibody - ab86671 from Abcam

Prices $394.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SIRT3 antibody (ab86671) at 1/1000 dilution + Mouse brain tissue lysate at 35 µg/mlSecondaryPeroxidase-conjugated goat anti-rabbit IgG (H+L) at 1/5000 dilution

Anti-SIRT3 antibody - ab56214 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SIRT3 antibody (ab56214) at 1 µg/ml + Liver (Mouse) Tissue Lysate at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

ANTI-MOUSE SIRT3 (C-TERM) antibody produced in rabbit - SAB1301489 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Mouse Sirt3 (C-term): <B>Cat. No. SAB1301489</B>: Mouse Sirt3 in Human breast carcinoma tissue with Mouse Sirt3 antibody (C-term) at 5 μg/mL.

Mouse-Sirt3-Antibody-C-term - AP6242b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Sirt3 Antibody (C-term) (Cat. #AP6242b) IHC analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Sirt3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Mouse Sirt3 Antibody - C-terminal region (OAAB16576) - OAAB16576 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Sirt3 antibody - orb36403 from Biorbyt

Prices $60.00, $187.00, $383.00
Sizes 5 μg (Trial size), 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal
Western blot analysis of mouse brain tissue lysates (35ug/lane) using Mouse Sirt3 antibody

SIRT3 antibody - PAB5930 from Acris Antibodies

Prices $420.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SIRT3 antibody - PAB9004 from Acris Antibodies

Prices $430.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Rabbit Anti-M Sirt3 (C-term) - 102-16696 from RayBiotech

Host Rabbit
Western blot analysis of lysate from mouse heart tissue lysate, using Mouse Sirt3 Antibody (C-term) (Cat# 102-16696). 102-16696 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.

Sirt3 Antibody - 42-388 from ProSci

Prices $315.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western blot analysis of Sirt3 in mouse heart lysate (35 μg protein in RIPA buffer) using Sirt3 Antibody at 0.3 μg/mL.

Anti-Sirtuin 3 antibody - STJ72597 from St John's Laboratory Ltd

Host Goat
Clonality Polyclonal

Sirt3 antibody (C-term) - STJ49871 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal
Clone RB25945

SIRT3, Polyclonal Antibody - MBS2520724 from MyBioSource

Prices $110.00, $150.00, $225.00, $360.00
Sizes 20 µl, 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

SIRT3, Polyclonal Antibody - MBS2527671 from MyBioSource

Prices $110.00, $150.00, $225.00, $360.00
Sizes 20 µl, 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

SIRT3, Polyclonal Antibody - MBS2529011 from MyBioSource

Prices $195.00, $270.00
Sizes 60 µl, 120 µl
Host Rabbit
Clonality Polyclonal

Anti-SIRT3 (aa 93-106) polyclonal antibody - DPABH-27454 from Creative Diagnostics

Host Goat
Clonality Polyclonal

Sirtuin 3, Polyclonal Antibody - MBS422614 from MyBioSource

Prices $300.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Polyclonal Antibody to Sirtuin 3 (SIRT3) - PAE913Mu01 from Cloud-clone

Host Rabbit
Clonality Polyclonal

Polyclonal Antibody to Sirtuin 3 (SIRT3) - PAE913Mu02 from Cloud-clone

Host Rabbit
Clonality Polyclonal

M Sirt3, Polyclonal Antibody - MBS9210535 from MyBioSource

Prices $155.00, $340.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal

Sirtuin 3 Antibody - abx129703 from Abbexa

Host Rabbit
Clonality Polyclonal

SIRT3 Antibody (F49520) - F49520 from NSJ Bioreagent

Prices $125.00, $299.00
Sizes 80 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide), 400 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide)
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysate from mouse heart tissue lysate using SIRT3 antibody diluted at 1:1000.

Sirtuin 3 (mouse) Polyclonal Antibody - CAE04814 from Biomatik

Prices $363.00
Sizes 100 μg
Host Goat
Clonality Polyclonal

Sirtuin 3 (SIRT3) Polyclonal Antibody - CAU22624 from Biomatik

Prices $114.00, $267.00, $382.00, $611.00
Sizes 10 μg, 50 μg, 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

M Sirt3 Antibody - 62-194 from ProSci

Prices $375.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western Blot at 1:64000 dilution + mouse liver lysate Lysates/proteins at 20 ug per lane.
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