TRPM7

Gene Symbol	TRPM7
Entrez Gene	54822
Alt Symbol	ALSPDC, CHAK, CHAK1, LTRPC7, LTrpC-7, TRP-PLIK
Species	Human
Gene Type	protein-coding
Description	transient receptor potential cation channel, subfamily M, member 7
Other Description	LTRPC ion channel family member 7|channel-kinase 1|long transient receptor potential channel 7|transient receptor potential cation channel subfamily M member 7|transient receptor potential-phospholipase C-interacting kinase
Swissprots	Q9NXQ2 Q8NBW2 Q96QT4 Q86VJ4 Q9BXB2 Q6ZMF5
Accessions	EAW77405 EAW77406 EAW77407 EAW77408 EAW77409 Q96QT4 AF346629 AAK19738 AK000124 BAA90958 AK075193 BAC11462 AK098584 AK172800 BAD18773 AY032950 AAK44211 BC028843 BC051024 AAH51024 BC128987 BC128988 BC169233 BC169234 BC169235 BP354541 DB127039 XM_005254486 XP_005254543 XM_005254487 XP_005254544 XM_011521712 XP_011520014 XR_931853 NM_001301212 NP_001288141 NM_017672 NP_060142
Function	Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF- induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). {ECO:0000269|PubMed:12887921, ECO:0000269|PubMed:15485879, ECO:0000269|PubMed:24316671}.
Subcellular Location	Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Top Pathways	Mineral absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TRPM7 peptide - ab22777 from Abcam Category Peptide Species Human

Human TRPM7 protein fragment - ab153385 from Abcam Category Protein Source Wheat germ Species Human

TRPM7 peptide - ab195344 from Abcam Category Peptide

TRPM7 Antibody Blocking Peptide - LS-E25233 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TRPM7 Antibody Blocking Peptide - LS-E9456 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TRPM7 Antibody Blocking Peptide - LS-E9457 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TRPM7 Blocking Peptide - NB500-243PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Rat

Recombinant Human TRPM7 Protein - H00054822-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TRPM7 Peptide - P3040 from Novus Biologicals Category Peptide Species Human

TRPM7 Peptide - P3039 from Novus Biologicals Category Peptide Species Human

TRPM7-CHAK1-Antibody-C-term-Blocking-peptide - BP8052b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TRPM7-CHAK1-Antibody-N-term-Blocking-peptide - BP8052a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TRPM7 blocking peptide - GTX20729-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat

TRPM7 Peptide - AC21-0058-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TRPM7 - H00054822-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TRPM7 - H00054822-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TRPM7 - P5520 from Acris Antibodies Category Protein Prices $1,010.00 Sizes 5 µg Species Human

TRPM7 Peptide - 46-531P from ProSci Category Peptide Species Mouse, Rat

Recombinant Transient Receptor Potential Cation Channel Subfamily M, Member 7 (TRPM7) - RPF837Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

TRPM7/LTRPC7, Peptide - MBS425263 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig

TRPM7 Recombinant Protein Antigen - NBP1-84493PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

TRPM7 Peptide, Human - M34GP16685H from Creative Peptides Category Peptide Source Synthetic. Species Human

TRPM7 (Extracellular region) - TX5655 from ECM Biosciences Category Peptide Prices $55.00 Sizes 50 μg

TRPM7 (a.a. 1484-1497) - TX5695 from ECM Biosciences Category Peptide Prices $55.00 Sizes 50 μg

TRPM7 Recombinant Protein Antigen - NBP2-58525PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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