TRPM7

Gene Symbol TRPM7
Entrez Gene 54822
Alt Symbol ALSPDC, CHAK, CHAK1, LTRPC7, LTrpC-7, TRP-PLIK
Species Human
Gene Type protein-coding
Description transient receptor potential cation channel, subfamily M, member 7
Other Description LTRPC ion channel family member 7|channel-kinase 1|long transient receptor potential channel 7|transient receptor potential cation channel subfamily M member 7|transient receptor potential-phospholipase C-interacting kinase
Swissprots Q9NXQ2 Q8NBW2 Q96QT4 Q86VJ4 Q9BXB2 Q6ZMF5
Accessions EAW77405 EAW77406 EAW77407 EAW77408 EAW77409 Q96QT4 AF346629 AAK19738 AK000124 BAA90958 AK075193 BAC11462 AK098584 AK172800 BAD18773 AY032950 AAK44211 BC028843 BC051024 AAH51024 BC128987 BC128988 BC169233 BC169234 BC169235 BP354541 DB127039 XM_005254486 XP_005254543 XM_005254487 XP_005254544 XM_011521712 XP_011520014 XR_931853 NM_001301212 NP_001288141 NM_017672 NP_060142
Function Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF- induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). {ECO:0000269|PubMed:12887921, ECO:0000269|PubMed:15485879, ECO:0000269|PubMed:24316671}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Top Pathways Mineral absorption

LTRPC7 CRISPR/Cas9 KO Plasmid (h) - sc-402820 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTRPC7 HDR Plasmid (h) - sc-402820-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTRPC7 Double Nickase Plasmid (h) - sc-402820-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTRPC7 Double Nickase Plasmid (h2) - sc-402820-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTRPC7 CRISPR Activation Plasmid (h) - sc-402820-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTRPC7 CRISPR Activation Plasmid (h2) - sc-402820-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTRPC7 Lentiviral Activation Particles (h) - sc-402820-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTRPC7 Lentiviral Activation Particles (h2) - sc-402820-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LTRPC7 siRNA (h) - sc-42662 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LTRPC7 shRNA Plasmid (h) - sc-42662-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LTRPC7 shRNA (h) Lentiviral Particles - sc-42662-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRPM7 RNAi - H00054822-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU015291 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® siRNA - SIHK2353 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2352 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2351 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2428 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2428 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09638 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09638

TRPM7 siRNA (Human) - CRJ0242 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRPM7 - MBS8210803 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TRPM7 (NM_017672.4) - SHH435696 from Creative biogene

Category siRNA
Species Reactivities Human

Human TRPM7 siRNA - orb270743 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRPM7 shRNA Plasmid (Human) - CHJ0242 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TRPM7 miRNA 3'UTR clone - MiUTR3H-07889 from Creative biogene

Species Reactivities Human
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