PROL1

Gene Symbol PROL1
Entrez Gene 58503
Alt Symbol BPLP, PRL1, opiorphin
Species Human
Gene Type protein-coding
Description proline rich, lacrimal 1
Other Description basic proline-rich lacrimal protein|basic proline-rich protein|proline-rich 1|proline-rich protein 1
Swissprots Q99935 A8MZ07 P85047
Accessions CAJ32190 CAJ34589 EAX05620 Q99935 BC092438 BC141465 AAI41466 BC148720 AAI48721 CD721906 CD722615 CD723077 CD723628 CK429697 CK430664 S83198 AAB46823 NM_001302807 NP_001289736 NM_021225 NP_067048 NR_126503
Function Opiorphin is an endogenous inhibitor of neprilysin and aminopeptidase N. Inhibits the breakdown of substance P, Mca-BK2 and Met-enkephalin by neprilysin in vitro with IC(50) values of 29 uM, 33 uM and 33 uM respectively. Inhibits the breakdown of Ala- pNA by aminopeptidase N in vitro with an IC(50) of 65 uM. Has a potent analgesic effect when administered to rats by intravenous injection. {ECO:0000269|PubMed:17101991}.
Subcellular Location Secreted {ECO:0000269|PubMed:17101991}.
Tissue Specificity Abundantly expressed in lacrimal gland where it found in the secretory endpieces. Also expressed at modest levels in the submandibular gland.

BPLP (S-14) - sc-160171 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

BPLP (P-13) - sc-160170 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BPLP (P-13): sc-160170. Western blot analysis of BPLP expression in ARPE-19 whole cell lysate.

Anti-Prol1 antibody - ab169504 from Abcam

Host Mouse
Clonality Polyclonal
All lanes : Anti-Prol1 antibody (ab169504) at 1/500 dilutionLane 1 : PROL1 transfected 293T lysateLane 2 : Non-transfected 293T lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-PROL1 Antibody (aa91-102) - LS-C154819 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PROL1 Antibody (aa30-42) - LS-C154820 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
PROL1 antibody (2.9 ug/ml) staining of cells in the submandibular salivary gland (SMG), but not in the sublingual salivary gland (SLG) in mouse.

PROL1 Antibody - NBP2-38075 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: PROL1 Antibody [NBP2-38075] - Staining of human salivary gland shows strong luminal membranous positivity in ducts.

PROL1 Antibody - H00058503-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: PROL1 Antibody [H00058503-B01] - analysis of PROL1 expression in transfected 293T cell line by PROL1 MaxPab polyclonal antibody. Lane 1: PROL1 transfected lysate (27.28 KDa). Lane 2: Non-transfected lysate.

C5AR1 Antibody (Phospho-Ser338) (OAAF00178) - OAAF00178 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

C5AR1 Antibody (OAAF00994) - OAAF00994 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PROL1 / BPLP antibody - H00058503-B01 from Acris Antibodies

Host Mouse
Clonality Polyclonal
Western Blot analysis of PROL1 expression in transfected 293T cell line (H00058503-T01) by PROL1 MaxPab polyclonal antibody. Lane 1: PROL1 transfected lysate(27.28 KDa). Lane 2: Non-transfected lysate.

Mouse anti-Human Prol1 polyclonal antibody - DPABH-08128 from Creative Diagnostics

Host Mouse
Clonality Polyclonal

Anti-PROL1 monoclonal antibody - DCABH-201305 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

PRL1, Monoclonal Antibody - MBS588017 from MyBioSource

Prices $555.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 29 or 269

Anti-PROL1 antibody produced in rabbit - HPA065711 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PROL1: <B>Cat. No. HPA065711</B>: Immunohistochemical staining of human salivary gland shows strong luminal membranous positivity in ducts.

PRL1 antibody - orb39116 from Biorbyt

Prices $187.00, $383.00
Sizes 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal
Western blot analysis of in mouse spleen tissue lysates (35ug/lane)using PRL1 antibody (primary antibody dilution at: 1:1000)

Anti-Mucin 10/Prol1 Antibody A14318 - A14318 from Boster Bio

Prices $290.00
Sizes 1
Host Goat
Clonality Polyclonal

Opiorphin (OPI) Monoclonal Antibody - CAU29340 from Biomatik

Prices $77.00, $182.00, $255.00, $365.00
Sizes 10 μg, 50 μg, 100 μg, 200 μg
Host Mouse
Clonality Monoclonal

C5AR1 Antibody - C30396 from Assay Biotechnology

Prices $175.00, $275.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal

Opiorphin (OPI), Monoclonal Antibody - MBS2051777 from MyBioSource

Prices $625.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Opiorphin (OPI), Monoclonal Antibody - MBS2051778 from MyBioSource

Prices $265.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Opiorphin (OPI), Monoclonal Antibody - MBS2051779 from MyBioSource

Prices $330.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Opiorphin (OPI), Monoclonal Antibody - MBS2051780 from MyBioSource

Prices $430.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Opiorphin (OPI), Monoclonal Antibody - MBS2051781 from MyBioSource

Prices $265.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Opiorphin (OPI), Monoclonal Antibody - MBS2051782 from MyBioSource

Prices $285.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Search more