PROL1

Gene Symbol	PROL1
Entrez Gene	58503
Alt Symbol	BPLP, PRL1, opiorphin
Species	Human
Gene Type	protein-coding
Description	proline rich, lacrimal 1
Other Description	basic proline-rich lacrimal protein|basic proline-rich protein|proline-rich 1|proline-rich protein 1
Swissprots	Q99935 A8MZ07 P85047
Accessions	CAJ32190 CAJ34589 EAX05620 Q99935 BC092438 BC141465 AAI41466 BC148720 AAI48721 CD721906 CD722615 CD723077 CD723628 CK429697 CK430664 S83198 AAB46823 NM_001302807 NP_001289736 NM_021225 NP_067048 NR_126503
Function	Opiorphin is an endogenous inhibitor of neprilysin and aminopeptidase N. Inhibits the breakdown of substance P, Mca-BK2 and Met-enkephalin by neprilysin in vitro with IC(50) values of 29 uM, 33 uM and 33 uM respectively. Inhibits the breakdown of Ala- pNA by aminopeptidase N in vitro with an IC(50) of 65 uM. Has a potent analgesic effect when administered to rats by intravenous injection. {ECO:0000269|PubMed:17101991}.
Subcellular Location	Secreted {ECO:0000269|PubMed:17101991}.
Tissue Specificity	Abundantly expressed in lacrimal gland where it found in the secretory endpieces. Also expressed at modest levels in the submandibular gland.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Prol1 full length protein - ab163685 from Abcam Category Protein Source Wheat germ Species Human

PROL1 Antibody Blocking Peptide - LS-E27571 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PROL1 Antibody Blocking Peptide - LS-E27572 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PROL1 Protein - H00058503-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Prol1 Immunizing peptide - orb66325 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

PROL1 / BPLP - H00058503-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

PROL1 fusion protein - ag17858 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Proline-rich protein 1(PROL1) - CSB-YP857463HU CSB-EP857463HU CSB-BP857463HU CSB-MP857463HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Opiorphin Protein - abx165789 from Abbexa Category Protein Source Human Species Human

Opiorphin Protein - abx165790 from Abbexa Category Protein Source Human Species Human

Proline-rich protein 1 (PROL1), Recombinant Protein - MBS1412664 from MyBioSource Category Protein Prices $980.00, $980.00, $1,200.00, $1,200.00, $1,480.00, $1,480.00, $1,945.00, $1,945.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PROL1 Recombinant Protein Antigen - NBP2-38075PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PROL1 Peptide, Human - M34GP12444H from Creative Peptides Category Peptide Source Synthetic. Species Human

Prol1 Immunizing peptide - orb66223 from Biorbyt Category Peptide

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