GABARAPL2

Gene Symbol GABARAPL2
Entrez Gene 11345
Alt Symbol ATG8, ATG8C, GATE-16, GATE16, GEF-2, GEF2
Species Human
Gene Type protein-coding
Description GABA(A) receptor-associated protein-like 2
Other Description MAP1 light chain 3 related protein|MAP1 light chain 3-related protein|gamma-aminobutyric acid receptor-associated protein-like 2|ganglioside expression factor 2|general protein transport factor p16|golgi-associated ATPase enhancer of 16 kDa
Swissprots Q6FG91 P60520
Accessions EAW95629 EAW95630 P60520 AB030710 BAB21548 AF077046 AAD27779 AF087848 AAK20400 AJ010569 CAA09249 AK289788 BAF82477 AK311266 AM393324 CAL38202 BC005985 AAH05985 BC014594 AAH14594 BC029601 AAH29601 BC040312 CR542217 CAG47013 DQ893101 ABM84027 DQ896373 ABM87372 NM_007285 NP_009216
Function Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. {ECO:0000250, ECO:0000269|PubMed:20418806, ECO:0000269|PubMed:23209295}.
Subcellular Location Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, autophagosome {ECO:0000269|PubMed:12507496, ECO:0000269|PubMed:15169837, ECO:0000269|PubMed:17580304, ECO:0000269|PubMed:19056683, ECO:0000269|PubMed:22311637}.
Tissue Specificity Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine. {ECO:0000269|PubMed:11146101, ECO:0000269|PubMed:11414770}.
Top Pathways GABAergic synapse, Regulation of autophagy

Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2), Human, ELISA Kit - CSB-EL009132HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

GABA (A) receptor-associated protein-like 2, ELISA Kit - MBS946953 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.039 ng/ml.
Range 0.156 ng/ml -10 ng/ml.

ELISA Kit for GABA-A Receptor Associated Protein Like Protein 2 (GABARAPL2) - SEJ288Hu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.061ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Gamma-aminobutyric acid receptor-associated protein-like 2(GABARAPL2) ELIS - CSB-EL009132HU from Cusabio

Sensitivity 0.039 ng/ml.
Range Request Information

ELISA Kit for GABA-A Receptor Associated Protein Like Protein 2 (GABARAPL2) - SEJ288Hu from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.061ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

GABA-A Receptor Associated Protein Like Protein 2 (GABARAPL2), ELISA Kit - MBS2025203 from MyBioSource

Category ELISA Kit
Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.061ng/mL.
Range 0.156-10ng/mL

Human GABARAPL2 / ATG8 ELISA Kit (Sandwich ELISA) - LS-F25550 from LifeSpan Bioscience

Category ELISA Kit
Prices $780.00
Sizes 1 plate
Sensitivity 0.061 ng/ml
Range 0.156-10 ng/ml

Human GABARAPL2 ELISA Kit - E015896 from Biobool

Category ELISA Kit
Sensitivity Typically less than 0.061ng/mL.

GABARAPL2 ELISA Kit (Human) (OKCD00560) - OKCD00560 from Aviva Systems Biology

Category ELISA Kit
Prices $545.00
Sizes 96 wells
Sensitivity < 0.061 ng/mL
Range 0.156-10 ng/mL

Human GABARAPL2 ELISA Kit - orb405939 from Biorbyt

Category ELISA Kit
Sensitivity 0.039 ng/ml.
Range 0.156 ng/ml-10 ng/ml
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