FBLN5

Gene Symbol	FBLN5
Entrez Gene	10516
Alt Symbol	ADCL2, ARCL1A, ARMD3, DANCE, EVEC, FIBL-5, UP50
Species	Human
Gene Type	protein-coding
Description	fibulin 5
Other Description	developmental arteries and neural crest EGF-like protein|fibulin-5|urine p50 protein
Swissprots	Q6UWA3 Q6IAL4 O75966 Q9UBX5
Accessions	CAF86416 CAJ30879 EAW81465 EAW81466 EAW81467 Q9UBX5 AA812956 AF093118 AAC62107 AF112152 AAD41768 AJ133490 CAB38568 AK074540 BAG51970 AK075147 BAG52073 AK094032 AK125600 AK307592 AL110148 AL546863 AY358898 AAQ89257 BC022280 AAH22280 BP338841 BX248290 CAD62618 BX537531 CR457140 CAG33421 DB263961 XM_005267267 XP_005267324 XM_011536356 XP_011534658 XM_011536357 XP_011534659 XM_011536358 XP_011534660 NM_006329 NP_006320
Function	Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823). {ECO:0000250|UniProtKB:Q9WVH9, ECO:0000269|PubMed:10428823, ECO:0000269|PubMed:18185537}.
Subcellular Location	Secreted {ECO:0000269|PubMed:16652333, ECO:0000269|PubMed:17035250, ECO:0000269|PubMed:20599547}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17035250}. Note=co-localizes with ELN in elastic fibers. {ECO:0000269|PubMed:17035250}.
Tissue Specificity	Expressed in skin fibroblasts (at protein level)(PubMed:17035250). Expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes (PubMed:10428823). {ECO:0000269|PubMed:10428823, ECO:0000269|PubMed:17035250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Fibulin-5 (H-60) - sc-30170 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Fibulin-5 (S-20) - sc-23062 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-Fibulin 5 antibody - ab53515 from Abcam Prices $376.00 Sizes 200 µl Host Goat Clonality Polyclonal

Anti-Fibulin 5 antibody - ab198212 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Fibulin 5 antibody - ab110045 from Abcam Prices $376.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Fibulin 5 antibody - ab56066 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Fibulin 5 antibody [1G6A4] - ab66339 from Abcam Prices $385.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 1G6A4

Anti-Fibulin 5 antibody [EPR4506] - ab109428 from Abcam Prices $379.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR4506

Anti-Fibulin 5 antibody [EPR685] - ab134136 from Abcam Prices $379.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR685

Anti-Fibulin 5 antibody - C-terminal - ab151298 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (aa327-448, Biotin) - LS-C299758 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (aa170-243, Biotin) - LS-C300008 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (aa277-448, Biotin) - LS-C300558 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (Internal, clone EPR685) - LS-C138191 from LifeSpan Bioscience Prices $475.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR685

Anti-FBLN5 / Fibulin 5 Antibody (aa505-518) - LS-C54842 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (aa215-326, Biotin) - LS-C300874 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (aa393-421) - LS-C159626 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (aa170-243, FITC) - LS-C302267 from LifeSpan Bioscience Prices $465.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (aa170-243) - LS-C293936 from LifeSpan Bioscience Prices $415.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (aa327-448) - LS-C293934 from LifeSpan Bioscience Prices $415.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (aa215-326) - LS-C293933 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (aa327-448, FITC) - LS-C303176 from LifeSpan Bioscience Prices $465.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (aa277-448, FITC) - LS-C302857 from LifeSpan Bioscience Prices $475.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (aa277-448) - LS-C293937 from LifeSpan Bioscience Prices $425.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBLN5 / Fibulin 5 Antibody (clone 1G6A4) - LS-C108813 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 1G6A4

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