FBLN5

Gene Symbol	FBLN5
Entrez Gene	10516
Alt Symbol	ADCL2, ARCL1A, ARMD3, DANCE, EVEC, FIBL-5, UP50
Species	Human
Gene Type	protein-coding
Description	fibulin 5
Other Description	developmental arteries and neural crest EGF-like protein|fibulin-5|urine p50 protein
Swissprots	Q6UWA3 Q6IAL4 O75966 Q9UBX5
Accessions	CAF86416 CAJ30879 EAW81465 EAW81466 EAW81467 Q9UBX5 AA812956 AF093118 AAC62107 AF112152 AAD41768 AJ133490 CAB38568 AK074540 BAG51970 AK075147 BAG52073 AK094032 AK125600 AK307592 AL110148 AL546863 AY358898 AAQ89257 BC022280 AAH22280 BP338841 BX248290 CAD62618 BX537531 CR457140 CAG33421 DB263961 XM_005267267 XP_005267324 XM_011536356 XP_011534658 XM_011536357 XP_011534659 XM_011536358 XP_011534660 NM_006329 NP_006320
Function	Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823). {ECO:0000250|UniProtKB:Q9WVH9, ECO:0000269|PubMed:10428823, ECO:0000269|PubMed:18185537}.
Subcellular Location	Secreted {ECO:0000269|PubMed:16652333, ECO:0000269|PubMed:17035250, ECO:0000269|PubMed:20599547}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17035250}. Note=co-localizes with ELN in elastic fibers. {ECO:0000269|PubMed:17035250}.
Tissue Specificity	Expressed in skin fibroblasts (at protein level)(PubMed:17035250). Expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes (PubMed:10428823). {ECO:0000269|PubMed:10428823, ECO:0000269|PubMed:17035250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FBLN5 / Fibulin 5 Antibody Blocking Peptide - LS-E5490 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FBLN5 / Fibulin 5 Antibody Blocking Peptide - LS-E26159 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FBLN5-Antibody-C-term-Blocking-Peptide - BP18010b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Fibulin 5 blocking peptide - GTX89251-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Recombinant Human Fibulin 5, CF - 3095-FB-025 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Gln24-Phe448, with a C-terminal 6-His tag

Goat anti FBLN5 antibody Immunizing peptide - orb16101 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

Human Fibulin 5 Protein - abx066649 from Abbexa Category Protein Source E.coli Species Human

Human Fibulin 5 Protein - abx066647 from Abbexa Category Protein Source E.coli Species Human

Fibulin 5 Peptide - AC21-0989-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Fibulin 5 (FBLN5), Human - 20-8695 from ARP American Research Products Category Protein Prices $509.00 Sizes 50 µg Source E.coli Species Human

Fibulin 5 (FBLN5), Human - 20-8696 from ARP American Research Products Category Protein Prices $509.00 Sizes 50 µg Source E.coli Species Human

Fibulin 5 Peptide - 45-595P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

FBLN5 fusion protein - ag2859 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

FBLN5 fusion protein - ag17091 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Fibulin 5 (FBLN5) - RPD153Hu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Fibulin 5 (FBLN5) - RPD153Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Fibulin 5 (FBLN5) - RPD153Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Fibulin 5 (FBLN5) - RPD153Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Fibulin 5 (FBLN5) - RPD153Hu02 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Fibulin-5(FBLN5) - CSB-YP866209HU CSB-EP866209HU CSB-BP866209HU CSB-MP866209HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Fibulin 5 Protein, CF - 3095-FB from R&D Systems Category Protein Prices $329.00 Sizes 25 µg Source Chinese Hamster Ovary cell line, CHO-derived Gln24-Phe448, with a C-terminal 6-His tag Species Human

Fibulin 5 (FBLN5) - RPU141485 from Biomatik Category Protein Prices $242.00, $484.00, $726.00 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

Fibulin 5 (FBLN5) - RPU141487 from Biomatik Category Protein Prices $242.00, $484.00, $726.00 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

Fibulin 5 Blocking Peptide - abx161620 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine

Fibulin-5 - TP304683 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

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