NTAN1

Gene Symbol	NTAN1
Entrez Gene	123803
Alt Symbol	PNAA, PNAD
Species	Human
Gene Type	protein-coding
Description	N-terminal asparagine amidase
Other Description	protein N-terminal Asn amidase|protein N-terminal asparagine amidase|protein N-terminal asparagine amidohydrolase|protein NH2-terminal asparagine deamidase|protein NTN-amidase
Swissprots	Q7Z4Z0 Q96AB6
Accessions	EAW54749 Q96AB6 AF092440 AAP97215 AK092915 BC017336 AAH17336 BF939373 DC383993 HQ447215 ADQ31702 HY036316 XM_011522355 XP_011520657 XM_011546694 XP_011544996 NM_001270766 NP_001257695 NM_001270767 NP_001257696 NM_173474 NP_775745
Function	Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N- terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position, nor on acetylated N- terminal peptidyl Asn. {ECO:0000269|PubMed:21375249}.
Subcellular Location	Cytoplasm {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NTAN1 full length protein - ab165200 from Abcam Category Protein Source Wheat germ Species Human

NTAN1 / PNAD Antibody Blocking Peptide - LS-E5291 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NTAN1 Protein - H00123803-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NTAN1-Antibody-C-term-Blocking-Peptide - BP17739b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NTAN1 - H00123803-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NTAN1 - H00123803-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NTAN1 fusion protein - ag10880 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

NTAN1 fusion protein - Ag9643 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human NTAN1, GST-tagged - NTAN1-1384H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Protein N-terminal asparagine amidohydrolase(NTAN1) - CSB-YP822176HU CSB-EP822176HU CSB-BP822176HU CSB-MP822176HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NTAN1 - TP305697 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NTAN1 Protein - NBP2-33615PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

NTAN1 Peptide, Human - M34GP10669H from Creative Peptides Category Peptide Source Synthetic. Species Human

Protein N-terminal asparagine amidohydrolase (NTAN1), Recombinant Protein - MBS1317795 from MyBioSource Category Protein Prices $1,065.00, $1,065.00, $1,300.00, $1,300.00, $1,670.00, $1,670.00, $2,135.00, $2,135.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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